June 2015
Volume 56, Issue 7
ARVO Annual Meeting Abstract  |   June 2015
Wide-field, high-definition retinal oximetry
Author Affiliations & Notes
  • David Bragason
    Ophthalmology, Landspitali University Hospital, Reykjavik, Iceland
  • Einar Stefansson
    Ophthalmology, Landspitali University Hospital, Reykjavik, Iceland
  • Footnotes
    Commercial Relationships David Bragason, None; Einar Stefansson, Oxymap (E), Oxymap (I), Oxymap (P)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 4413. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      David Bragason, Einar Stefansson; Wide-field, high-definition retinal oximetry. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):4413.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

To develop improved image processing and analysis methods to obtain retinal oximetry images with a wide field of view and increased spatial definition.


We use the Oxymap T1, a commercial dual-wavelength, spectrophotometric retinal oximeter (Oxymap, Reykjavik, Iceland). Using a custom developed plugin for ImageJ (NIH, Bethesda, MD, USA) and commercial image registration and montaging software (i2k Retina, DualAlign LLC, USA), we obtain detailed oxygen saturation maps of arbitrarily large regions of the eye fundus by montaging several snapshots into one image. The central specular reflection on retinal vessels is automatically analyzed and eliminated using custom image processing algorithms.


Our retinal oximetry images show retinal vessel oxygen saturation patterns of larger regions of the retina than was previously possible. Previous studies using the Oxymap T1 retinal oximeter have used single 50-degree field of view images centered on the optic disc to obtain a measure of the net oxygen balance of retinal arterioles and venules. Our new method combines several 50, 35 or 20-degree snapshots into an oximetry image with a wider field of view and higher spatial definition of larger areas including the optic disc, macula and more peripheral areas. Vessels supplying the macula have higher venular saturation values and lower arteriovenous difference than other parts of the retina.


We have developed a new method to process retinal oximetry images from the Oxymap T1 to obtain wide-field, increased spatial definition oxygen saturation maps of the retina. Increased field of view shows regional variability in oxygen levels. Increased spatial definition shows a systematic intravascular variability in oxygen saturation.  

50-degree oximetry image
50-degree oximetry image
Spectral fundus image montage
Spectral fundus image montage


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.