November 1972
Volume 11, Issue 11
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Articles  |   November 1972
Tetrahydrotriamcinolone and Triamcinolone I. Ocular Penetration
JOEL SUGAR; RONALD M. BURDE; ALAN SUGAR; STEPHEN R. WALTMAN; K. J. KRIPALANI; IRVING WELIKY; BERNARD BECKER
Author Affiliations
  • JOEL SUGAR
    Department of Ophthalmology, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Mo. 63110, and the Squibb Institute for Medical Research, New Brunswick, N.J.
  • RONALD M. BURDE
    Department of Ophthalmology, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Mo. 63110, and the Squibb Institute for Medical Research, New Brunswick, N.J.
  • ALAN SUGAR
    Department of Ophthalmology, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Mo. 63110, and the Squibb Institute for Medical Research, New Brunswick, N.J.
  • STEPHEN R. WALTMAN
    Department of Ophthalmology, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Mo. 63110, and the Squibb Institute for Medical Research, New Brunswick, N.J.
  • K. J. KRIPALANI
    Department of Ophthalmology, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Mo. 63110, and the Squibb Institute for Medical Research, New Brunswick, N.J.
  • IRVING WELIKY
    Department of Ophthalmology, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Mo. 63110, and the Squibb Institute for Medical Research, New Brunswick, N.J.
  • BERNARD BECKER
    Department of Ophthalmology, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, Mo. 63110, and the Squibb Institute for Medical Research, New Brunswick, N.J.
Investigative Ophthalmology & Visual Science November 1972, Vol.11, 890-893. doi:
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      JOEL SUGAR, RONALD M. BURDE, ALAN SUGAR, STEPHEN R. WALTMAN, K. J. KRIPALANI, IRVING WELIKY, BERNARD BECKER; Tetrahydrotriamcinolone and Triamcinolone I. Ocular Penetration. Invest. Ophthalmol. Vis. Sci. 1972;11(11):890-893.

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Abstract

Triamcinolone (TA) and tetrahydrotriamcinolone (THTA) are very similar in structure, but only one, TA, consistently raises intraocular pressure in susceptible individuals. It has been postulated that these differences are due to differing penetration qualities. In the present study, using anterior chamber paracentesis in human eyes, these drugs were very similar in ocular penetration.

Copyright 1972 The Association for Research in Vision and Ophthalmology, Inc.
Copyright © 2024 Association for Research in Vision and Ophthalmology.
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