October 1974
Volume 13, Issue 10
Free
Articles  |   October 1974
Histochemical Evidence of Cyclic Nucleotide Phosphodiesterase in Photoreceptor Outer Segments
Author Affiliations
  • RICHARD M. ROBB
    Department of Ophthalmology, Children's Hospital Medical Center and Harvard Medical School, Boston, Mass.
Investigative Ophthalmology & Visual Science October 1974, Vol.13, 740-747. doi:https://doi.org/
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      RICHARD M. ROBB; Histochemical Evidence of Cyclic Nucleotide Phosphodiesterase in Photoreceptor Outer Segments. Invest. Ophthalmol. Vis. Sci. 1974;13(10):740-747. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
This content is PDF only. Please click on the PDF icon to access.
Abstract

A histochemical demonstration of cyclic 3',5'-nucleotide phosphodiesterase in retinal photoreceptor outer segments is reported for the first time. The enzyme appears to be located on outer segment lamellae. It is not found in adjacent inner segment or nuclear regions. This histochemical localization is consistent with previously reported biochemical studies showing high phosphodiesterase activity in preparations of isolated rod outer segments.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×