October 1974
Volume 13, Issue 10
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Articles  |   October 1974
Varicella Dendritic Keratitis
Author Affiliations
  • ADAM BORIT
    Estelle Doheny Eye Foundation Laboratory and the University of Southern California, Department of Ophthalmology Los Angeles
  • JOHN PENTELEI-MOLNAR
    Estelle Doheny Eye Foundation Laboratory and the University of Southern California, Department of Ophthalmology Los Angeles
  • RICHARD LAZARO
    Estelle Doheny Eye Foundation Laboratory and the University of Southern California, Department of Ophthalmology Los Angeles
Investigative Ophthalmology & Visual Science October 1974, Vol.13, 764-770. doi:https://doi.org/
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      ADAM BORIT, JOHN PENTELEI-MOLNAR, RICHARD LAZARO; Varicella Dendritic Keratitis. Invest. Ophthalmol. Vis. Sci. 1974;13(10):764-770. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Atypical dendritic keratitis has been described following herpes zoster infection. This is the first reported case of atypical dendritic keratitis following classical varicella infection. It also provides the first light and electron microscopic description of the varicella-zoster dendritic corneal lesion. The diagnosis is substantiated by the clinical appearance of the lesion and by the presence of serum antibody titers against varicella-zoster but not against herpes simplex. Cultures were negative for both viruses. The grayish intra-epithelial plaque-like appearance of the varicella-zoster dendritic lesion consists of unhealthy and dying cells in the middle layers of the corneal epithelium. These cells show a relatively sparse population of herpes-type virus particles.

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