August 1974
Volume 13, Issue 8
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Articles  |   August 1974
Feline Central Retinal Degeneration
Author Affiliations
  • R. W. BELLHORN
    Department of Ophthalmology, Montefiore Hospital and Medical Center/Albert Einstein College of Medicine, 111 E. 210 St., Bronx, N. Y. 10467
  • G. D. AGUIRRE
    Section of Ophthalmology, the School of Veterinary Medicine, University of Pennsylvania 3800 Spruce St., Philadelphia, Pa. 19174
  • M. B. BELLHORN
    Department of Ophthalmology, Montefiore Hospital and Medical Center/Albert Einstein College of Medicine, 111 E. 210 St., Bronx, N. Y. 10467
Investigative Ophthalmology & Visual Science August 1974, Vol.13, 608-616. doi:
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      R. W. BELLHORN, G. D. AGUIRRE, M. B. BELLHORN; Feline Central Retinal Degeneration. Invest. Ophthalmol. Vis. Sci. 1974;13(8):608-616.

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      © 2015 Association for Research in Vision and Ophthalmology.

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Abstract

Seven domestic cats with feline central retinal degeneration (FCRD) were investigated by ophthalmoscopy, fluorescein angiography, electroretinography, and light and electron microscopy. Little or no increase in lesion size was observed ophthalmoscopically over periods as long as four years. Five cats showed normal rod electroretinographic (ERG) responses and abnormal cone responses. In one cat both rod and cone responses were abnormal and in one cat neither rod nor cone responses were abnormal. Electron microscopic studies of one cat with an abnormal cone ERG showed outer segment lamellar disorganization in cones outside of the focal lesion. In the FCRD-affected cat with no ERG abnormalities, ultrastnicture of cones outside the focal lesion was normal. Fluorescein angiography did not demonstrate abnormalities of apparent etiologic significance.

Copyright 1974 The Association for Research in Vision and Ophthalmology, Inc.
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