December 1964
Volume 3, Issue 6
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Articles  |   December 1964
Catechol-O-methyl Transferase and Monoamine Oxidase Activity in the Ocular Tissues of Albino Rabbits
Author Affiliations
  • STEPHEN WALTMAN
    Section of Ophthalology, Department of Surgery, Yale University School of Medicine, New Haven, Conn.
  • MARVIN SEARS
    Section of Ophthalology, Department of Surgery, Yale University School of Medicine, New Haven, Conn.
Investigative Ophthalmology & Visual Science December 1964, Vol.3, 601-605. doi:
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      STEPHEN WALTMAN, MARVIN SEARS; Catechol-O-methyl Transferase and Monoamine Oxidase Activity in the Ocular Tissues of Albino Rabbits. Invest. Ophthalmol. Vis. Sci. 1964;3(6):601-605.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The distribution of catechol-O-methyl transferase and monoamine oxidase activity in the ocular tissues of albino rabbits has been determined with a radioactive tracer assay. The distribution of the former varied in the different tissues within a restricted range whereas the distribution of monoamine oxidase activity exhibited larger variations. Sympathetic denervation did not appear to affect catechol-O-methyl transferase levels although moderate decreases in MAO levels were observedone week after denervation. The possible role of these enzymes for catecholamine metabolism in the eye is briefly discussed.

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