October 2012
Volume 53, Issue 11
Free
Letters to the Editor  |   October 2012
Spectral-Domain Optical Coherence Tomography as a Noninvasive Method to Assess Damaged and Regenerating Adult Zebrafish Retinas
Author Affiliations & Notes
  • Joel S Schuman
    UPMC Eye Center, University of Pittsburgh School of Medicine, Eye & Ear Institute, Pittsburgh, Pennsylvania; the
  • Larry Kagemann
    UPMC Eye Center, University of Pittsburgh School of Medicine, Eye & Ear Institute, Pittsburgh, Pennsylvania; the
    Professor of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania; and the
  • Hiroshi Ishikawa
    UPMC Eye Center, University of Pittsburgh School of Medicine, Eye & Ear Institute, Pittsburgh, Pennsylvania; the
    Professor of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania; and the
  • Gadi Wollstein
    UPMC Eye Center, University of Pittsburgh School of Medicine, Eye & Ear Institute, Pittsburgh, Pennsylvania; the
Investigative Ophthalmology & Visual Science October 2012, Vol.53, 7315. doi:10.1167/iovs.12-10925
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      Joel S Schuman, Larry Kagemann, Hiroshi Ishikawa, Gadi Wollstein; Spectral-Domain Optical Coherence Tomography as a Noninvasive Method to Assess Damaged and Regenerating Adult Zebrafish Retinas. Invest. Ophthalmol. Vis. Sci. 2012;53(11):7315. doi: 10.1167/iovs.12-10925.

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      © ARVO (1962-2015); The Authors (2016-present)

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We read with interest “Spectral-Domain Optical Coherence Tomography (SD-OCT) as a Noninvasive Method to Assess Damaged and Regenerating Adult Zebrafish Retinas,” by Bailey and coauthors. 1 The article was interesting, but we would like to correct one item in the manuscript. While the authors have claimed their work as novel ("Although SD-OCT has been used to noninvasively image the retinas of a variety of different species, it has not been shown to accurately examine a tissue as small as the zebrafish eye.”), Kagemann and coauthors, 2 in 2008, reported spectral domain OCT in zebrafish eyes in Molecular Vision. Further, the Kagemann study 2 examined eyes (in addition to brain, heart, ear, and spine) of zebrafish embryos as young as 24 hours post fertilization, using both structural and functional spectral domain OCT imaging. Ironically, while Kagemann et al. 2 studied zebrafish embryos, the authors of the current study made their measurements in adult fish, while making the claim regarding “tissue as small as a zebrafish eye.” 
It would be best for authors to carefully study the literature prior to writing any paper, in particular when claiming primacy. 
References
Bailey TJ Davis DH Vance JE Hyde DR. Spectral-domain optical coherence tomography as a noninvasive method to assess damaged and regenerating adult zebrafish retinas. Invest Ophthalmol Vis Sci . 2012;53:3126–3138. [CrossRef] [PubMed]
Kagemann L Ishikawa H Zou J Repeated, noninvasive, high resolution spectral domain optical coherence tomography imaging of zebrafish embryos. Mol Vis . 2008;14:2157–2170. [PubMed]
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