December 1966
Volume 5, Issue 6
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Articles  |   December 1966
Venous pressure opposing aqueous outflow in patients with and without chronic open-angle glaucoma
Author Affiliations
  • JEROME W. BETTMAN, Jr.
    Francis I. Proctor Foundation for Research in Ophthalmology, and the Department of Ophthalmology, University of California School of Medicine San Francisco, Calif.
  • W. K. MCEWEN
    Francis I. Proctor Foundation for Research in Ophthalmology, and the Department of Ophthalmology, University of California School of Medicine San Francisco, Calif.
  • EARLE H. MCBAIN
    Francis I. Proctor Foundation for Research in Ophthalmology, and the Department of Ophthalmology, University of California School of Medicine San Francisco, Calif.
Investigative Ophthalmology & Visual Science December 1966, Vol.5, 624-635. doi:
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      JEROME W. BETTMAN, W. K. MCEWEN, EARLE H. MCBAIN; Venous pressure opposing aqueous outflow in patients with and without chronic open-angle glaucoma . Invest. Ophthalmol. Vis. Sci. 1966;5(6):624-635.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Three groups of patients (those with chronic open-angle glaucoma, glaucoma suspects, and normals) were subjected to both tonography and suction cup analysis. The data, analyzed by an electrical model of the eye, showed that (1) venous pressure opposing aqueous outflow is higher in patients with chronic open-angle glaucoma and in glaucoma suspects than in normal patients; and (2) lack of pressure rise during the time that a perilimbal suction cup is applied to the eye may not be the result of faulty technique, as has been previously assumed, but may indicate inflow less than the stress relaxation of the ocular coats. The results confirm that (1) patients with chronic open-angle glaucoma have a decreased facility of outflow, independent of other parameters; and (2) patients on both acetazolamide and epinephrine therapy have a decreased aqueous production

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