April 1969
Volume 8, Issue 2
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Articles  |   April 1969
Electron Microscopic Study of Galactose-Induced Cataract
Author Affiliations
  • TOICHIRO KUWABARA
    Howe Laboratory of Ophthalmology, Harvard University Medical School and Massachusetts Eye and Ear Infirmary, Boston, Mass. 02114
  • JIN H. KINOSHITA
    Howe Laboratory of Ophthalmology, Harvard University Medical School and Massachusetts Eye and Ear Infirmary, Boston, Mass. 02114
  • DAVID G. COGAN
    Howe Laboratory of Ophthalmology, Harvard University Medical School and Massachusetts Eye and Ear Infirmary, Boston, Mass. 02114
Investigative Ophthalmology & Visual Science April 1969, Vol.8, 133-149. doi:
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      TOICHIRO KUWABARA, JIN H. KINOSHITA, DAVID G. COGAN; Electron Microscopic Study of Galactose-Induced Cataract. Invest. Ophthalmol. Vis. Sci. 1969;8(2):133-149.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Cataractous lenses induced by galactose feeding were studied electron microscopically. The early changes were increased reactivity of the epithelium, edema of the lens cells, and intercellular cyst formation in the bow and posterior zones. These changes continued with further feeding of galactose until the lens cells became irreversibly damaged. The reactive epithelial cells formed marked cell proliferations.

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