June 1968
Volume 7, Issue 3
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Articles  |   June 1968
Distribution of 5,5-Dimethyl-2,4-Oxazolidinedione (DMO) in Intraocular Fluids
Author Affiliations
  • MARGUERITE A. CONSTANT
    Department of Ophthalmology and the Oscar Johnson Institute, Washington University Medical School St. Louis, Mo.
Investigative Ophthalmology & Visual Science June 1968, Vol.7, 334-346. doi:
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      MARGUERITE A. CONSTANT; Distribution of 5,5-Dimethyl-2,4-Oxazolidinedione (DMO) in Intraocular Fluids . Invest. Ophthalmol. Vis. Sci. 1968;7(3):334-346.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The kinetics of penetration of DMO into intraocular fluids at different plasma levels or after the administration of probenecid or dichlorphenamide have been studied. Many similarities were found to other systems which have been studied. The data provided further evidence for the probability that DMO is secreted out of the eye and that this mechanism is inhibited by probenecid and dichlorphenamide.

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