June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Polarization Sensitive Optical Coherence Tomography with Retinal Tracking and Frame averaging
Author Affiliations & Notes
  • Mitsuro Sugita
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria
    Canon Inc., Tokyo, Japan
  • Stefan Zotter
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria
  • Michael Pircher
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria
  • Tomoyuki Makihira
    Canon Inc., Tokyo, Japan
  • Kenichi Saito
    Canon Inc., Tokyo, Japan
  • Nobuhiro Tomatsu
    Canon Inc., Tokyo, Japan
  • Christoph Hitzenberger
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria
  • Footnotes
    Commercial Relationships Mitsuro Sugita, Canon Inc. (E); Stefan Zotter, Canon Inc. (F); Michael Pircher, None; Tomoyuki Makihira, Canon (E); Kenichi Saito, Canon Inc. (E); Nobuhiro Tomatsu, Canon Inc. (E); Christoph Hitzenberger, Canon Inc. (F), Canon Inc. (C)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 1475. doi:
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      Mitsuro Sugita, Stefan Zotter, Michael Pircher, Tomoyuki Makihira, Kenichi Saito, Nobuhiro Tomatsu, Christoph Hitzenberger; Polarization Sensitive Optical Coherence Tomography with Retinal Tracking and Frame averaging. Invest. Ophthalmol. Vis. Sci. 2013;54(15):1475.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To show the performance of a new polarization sensitive OCT system (PS-OCT) combined with retinal tracking functionality and frame averaging under the influence of a large eye motion.

Methods: A new polarization maintaining fiber based PS-OCT system combined with a positional detection optical unit for retinal tracking was built. The PS-OCT system operates at 70kHz A-scan rate and supports scan angles of up to 28°x20°. To test the performance of the retinal tracker (operating at 60Hz) healthy volunteers eyes with no dilation were imaged. For inducing eye motion, the volunteer was asked to follow a moving fixation target (1mm diameter cycle at 0.5Hz on the retina). 3D volume scans and a series of 80 stationary B-scans were recorded. A series of 1,5,10,20,30 and 50 of these stationary intensity and retardation B-scans were averaged. For a quantitative evaluation of the data, an evaluation window was placed in the retinal nerve fiber layer and the mean and standard deviation of the retardation was calculated.

Results: A visual examination of the 3D volume scan showed that the retinal tracker performs well even in the case of the large artificially induced eye motion. The standard deviation of the retardation values within the evaluation window was 6.66° in the case of a single retardation B-scan. This standard deviation decreased to 0.97° after the averaging of 50 B-scans, which indicates the successful reduction of motion artifacts.

Conclusions: To the best of our knowledge, this work presents the first realization of PS-OCT combined with retinal tracking. First measurement results on healthy volunteers showed that the tracking performs well even in the case of large eye motion.

Keywords: 630 optical properties • 522 eye movements  
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