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Adam Carver, Robert Leonard; Observational and Surgical Course of Vitreomacular Traction Syndrome. Invest. Ophthalmol. Vis. Sci. 2013;54(15):1557.
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© ARVO (1962-2015); The Authors (2016-present)
This study analyzed the course of surgical and conservative management of vitreomacular traction syndrome (VMT). There is a paucity of literature evaluating observed VMT cases.
This case-control study is a retrospective chart review of 75 symptomatic cases VMT, followed over the available course of the disease. Patients were divided primarily into those requiring surgical intervention and those that were observed. Data collected included patient demographics, visual acuity, and OCT results.
Average age of VMT patients was 69.4 yrs., and 72.0% were female. Overall, 37.3% (28/75) of patients required surgical intervention. Excluding all surgical cases, spontaneous resolution was seen in 40.4% (19/47) of observed cases. Averaging all cases of VMT showed a statistically significant increase in vision (20/49 to 20/36, p = 0.015), and the observed cases of VMT did not get worse (20/37 vs. 20/31, p = 0.1307). When comparing cystic changes on OCT, the surgical group showed statistical significance (96.2% vs. 23.1%, p = 0.0109). 10.8% (8/75) of VMT patients progressed to a macular hole.
VMT is primarily a disease of females in the sixth decade. Symptomatic observed cases of VMT not meeting surgical criteria did not get worse, and these cases can be safely observed.
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