June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Comparison of ultra wide-field fluorescein angiography using the Optos® P200Tx and Heidelberg Spectralis® the non-contact wide-angle lens
Author Affiliations & Notes
  • George Parlitsis
    Department of Ophthalmology, Weill Cornell Medical College, New York, NY
  • Matthew Witmer
    Department of Ophthalmology, Weill Cornell Medical College, New York, NY
  • Sarju Patel
    Department of Ophthalmology, Weill Cornell Medical College, New York, NY
  • Szilard Kiss
    Department of Ophthalmology, Weill Cornell Medical College, New York, NY
  • Footnotes
    Commercial Relationships George Parlitsis, None; Matthew Witmer, None; Sarju Patel, None; Szilard Kiss, Alcon (F), Alimera (F), Alimera (C), Alimera (R), Allergan (F), Allergan (C), Allergan (R), Genentech (F), Genentech (C), Genentech (R), Regeneron (F), Regeneron (C), Regeneron (R), Optos (F), Optos (C), Optos (R), Eytech (C), Merge/OIS (C), Merge/OIS (I)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 16. doi:
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    • Get Citation

      George Parlitsis, Matthew Witmer, Sarju Patel, Szilard Kiss; Comparison of ultra wide-field fluorescein angiography using the Optos® P200Tx and Heidelberg Spectralis® the non-contact wide-angle lens. Invest. Ophthalmol. Vis. Sci. 2013;54(15):16.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

Although peripheral retinal evaluation with ultra wide-field (UWF) fundus photography and fluorescein angiography (FA) is becoming increasingly important in the diagnosis, monitoring and treatment of numerous retinal disorders, a direct assessment of the area of the retina imaged among various wide-field devices is lacking. The purpose of this study is to determine the extent of the peripheral retina visualized on UWF-FA using the Optos® P200Tx and Heidelberg Spectralis® non-contact wide-field lens.

 
Methods
 

Primary gaze, single-shot images of 10 eyes of 5 patients who underwent UWF-FA with both the Optos® P200Tx and Heidelberg Spectralis® non-contact wide-field lens were superimposed, taking into account differences in magnification and peripheral retinal distortion seen on the Optos®. The area of imaged retina was outlined and quantified using Adobe® Photoshop® software. The superior, inferior, nasal and temporal retina visualized was determined and compared between the two devices.

 
Results
 

The Optos® 200Tx captured a total retinal area averaging 146,562 pixels, ranging from 116,998 to 205,833 pixels due to lid and lash artifact; the total area of the retina visualized with Heidelberg Spectralis® was 101,786 pixels, ranging from 73,424 to 116,319 pixels. The average area of individual quadrants imaged by Optos® compared to Heidelberg® was: Superior (32,373 vs. 32,789), Inferior (24,665 vs. 26,117), Temporal (47,948 vs. 20,645), and Nasal (46,374 vs. 22,234).

 
Conclusions
 

UWF-FA with both the Optos® and Spectralis® system are excellent imaging devices which allow for visualization of peripheral retinal pathology beyond that which could be seen on the traditional ETDRS 7-standard fields. On a single shot primary-gaze image, the Optos® visualizes a larger total retinal surface area compared to the Heidelberg®. Optos® captures a wider view temporally and nasally; however, the effect of the eyelids and lashes considerably limits high-quality view to the far superior and inferior periphery with the Optos®. The Heidelberg® non-contact wide-field lens was able to image peripheral pathology located superiorly and inferiorly which may be missed with an Optos® UWF-FA. The ability for eye steering to visualize even more of the peripheral retina was not evaluated in this study.

 
 
Overlayed Optos® P200Tx and Heidelberg Spectralis® the non-contact wide-angle lens images
 
Overlayed Optos® P200Tx and Heidelberg Spectralis® the non-contact wide-angle lens images
 
Keywords: 552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • 550 imaging/image analysis: clinical  
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