June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Biomechanical properties of the cornea and graft after Descemet's stripping endothelial keratoplasty
Author Affiliations & Notes
  • Saima Qureshi
    Ophthalmology, Howard University Hospital, Washington, DC
  • Ninita Brown
    Ophthalmology, Howard University Hospital, Washington, DC
  • Naazli Shaikh
    Ophthalmology, Howard University Hospital, Washington, DC
    Ophthalmology, Veterans Affairs Medical Center, Orlando, FL
  • Footnotes
    Commercial Relationships Saima Qureshi, None; Ninita Brown, None; Naazli Shaikh, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 1634. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Saima Qureshi, Ninita Brown, Naazli Shaikh; Biomechanical properties of the cornea and graft after Descemet's stripping endothelial keratoplasty. Invest. Ophthalmol. Vis. Sci. 2013;54(15):1634.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: To measure the biomechanical properties of the cornea and graft after Descemet’s stripping endothelial keratoplasty (DSEK) using the ocular response analyzer (ORA) and to evaluate the correlation between corneal compensated intraocular pressure (IOPcc) and Goldmann applanated intraocular pressure (IOP GAT).

Methods: A cross-sectional study of 7 eyes of 7 patients with Fuch’s endothelial dystrophy who underwent DSEK with at least 6 months of follow up. Corneal hysteresis (CH), cornea resistance factor (CRF), cornea compensated intraocular pressure (IOPcc) were measured using the ORA. At the same visit, IOP GAT was obtained. A comparison of post-DSEK ORA parameters to those of non-diseased corneas and the correlation of IOPcc to IOP GAT were investigated.

Results: Mean patient age was 71.85±11.48 years. The mean follow up period was 25.71±12.72 months. Mean CH and CRF were 9.90±1.40 mmHg and 9.61±1.16mmHg, respectively. The difference of CH and CRF of post-DSEK corneas were not found to be significant when compared to CH and CRF values of non-diseased corneas1 (p value= 0.5745, unpaired t test). Cornea-compensated intraocular pressure was not found to be significantly different when compared with IOP GAT (p value= 0.3731, paired t test).

Conclusions: The biomechanical properties of the cornea and graft after DSEK are found to be within the range of values of non-diseased corneas. The difference between IOPcc and IOP GAT after DSEK was not found to be significant. 1 Values for non-diseased corneas: CH=10.25±1.6, n=100; CRF=10.25±1.85, n=100. Source: Montard R, Kopito R, Touzeau O, Allouch C, Letaief I, Borderie V, Laroche L. Ocular response analyzer: feasibility study and correlation with normal eyes. J Fr Ophtalmol. 2007 Dec.30(10):978-84.

Keywords: 479 cornea: clinical science  
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×