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Saima Qureshi, Ninita Brown, Naazli Shaikh; Biomechanical properties of the cornea and graft after Descemet's stripping endothelial keratoplasty. Invest. Ophthalmol. Vis. Sci. 2013;54(15):1634.
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To measure the biomechanical properties of the cornea and graft after Descemet’s stripping endothelial keratoplasty (DSEK) using the ocular response analyzer (ORA) and to evaluate the correlation between corneal compensated intraocular pressure (IOPcc) and Goldmann applanated intraocular pressure (IOP GAT).
A cross-sectional study of 7 eyes of 7 patients with Fuch’s endothelial dystrophy who underwent DSEK with at least 6 months of follow up. Corneal hysteresis (CH), cornea resistance factor (CRF), cornea compensated intraocular pressure (IOPcc) were measured using the ORA. At the same visit, IOP GAT was obtained. A comparison of post-DSEK ORA parameters to those of non-diseased corneas and the correlation of IOPcc to IOP GAT were investigated.
Mean patient age was 71.85±11.48 years. The mean follow up period was 25.71±12.72 months. Mean CH and CRF were 9.90±1.40 mmHg and 9.61±1.16mmHg, respectively. The difference of CH and CRF of post-DSEK corneas were not found to be significant when compared to CH and CRF values of non-diseased corneas1 (p value= 0.5745, unpaired t test). Cornea-compensated intraocular pressure was not found to be significantly different when compared with IOP GAT (p value= 0.3731, paired t test).
The biomechanical properties of the cornea and graft after DSEK are found to be within the range of values of non-diseased corneas. The difference between IOPcc and IOP GAT after DSEK was not found to be significant. 1 Values for non-diseased corneas: CH=10.25±1.6, n=100; CRF=10.25±1.85, n=100. Source: Montard R, Kopito R, Touzeau O, Allouch C, Letaief I, Borderie V, Laroche L. Ocular response analyzer: feasibility study and correlation with normal eyes. J Fr Ophtalmol. 2007 Dec.30(10):978-84.
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