June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Femtosecond Laser-Assisted Deep Anterior Lamellar Keratoplasty with Zig-zag Configuration: Initial Outcomes
Author Affiliations & Notes
  • Ijeoma Asota
    Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA
  • Matthew Wade
    Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA
  • John Xie
    Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA
  • Sumit Garg
    Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA
  • Roger Steinert
    Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA
  • Marjan Farid
    Gavin Herbert Eye Institute, University of California Irvine, Irvine, CA
  • Footnotes
    Commercial Relationships Ijeoma Asota, None; Matthew Wade, None; John Xie, None; Sumit Garg, None; Roger Steinert, Abbott Medical Optics (C), OptiMedica (C), ReVision Optics (C), WaveTec (C); Marjan Farid, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 1751. doi:
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    • Get Citation

      Ijeoma Asota, Matthew Wade, John Xie, Sumit Garg, Roger Steinert, Marjan Farid; Femtosecond Laser-Assisted Deep Anterior Lamellar Keratoplasty with Zig-zag Configuration: Initial Outcomes. Invest. Ophthalmol. Vis. Sci. 2013;54(15):1751.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To report the early refractive results and clinical outcomes of deep anterior lamellar keratoplasty (DALK) performed using the femtosecond laser with the zig-zag incision configuration.

 
Methods
 

30 consecutive eyes underwent femtosecond laser assisted DALK with zig-zag configuration. Clinical records were reviewed retrospectively. Corrected distance visual acuity (CDVA), manifest and topographic astigmatism, and complications were reviewed.

 
Results
 

In 26 eyes, a big-bubble was successfully achieved. The remaining 4 eyes required dissection down to a very thin residual stromal bed. Postoperative follow-up ranged from 3 months (n=28) to 2.5 years (n=3). At post-operative month 3, mean CDVA was 20/30 (range 20/20-20/60), mean manifest astigmatism was 3.5 D (range 1.25-6 D), and mean topographic astigmatism was 4.23 D (range 1.1-9.25 D). These outcomes remained stable throughout the follow up period. Complications included suture revision at post-operative month 3 for wound gape in one patient, and an episode of stromal rejection in one patient.

 
Conclusions
 

Visual outcomes of femtosecond laser-assisted zig-zag DALK are similar to our results with zig-zag full thickness penetrating keratoplasty. In addition, this technique offers a decreased risk of endothelial rejection in healthy eyes compared to penetrating keratoplasty.

 
Keywords: 741 transplantation • 578 laser • 479 cornea: clinical science  
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