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Naoki Tojo, Keiichi Mitarai, Miyako Oka, Akio Miyakoshi, Atsushi Hayashi, ; Comparison of fluctuations of intraocular pressure before and after selective laser trabeculoplasty in normal tension glaucoma. Invest. Ophthalmol. Vis. Sci. 2013;54(15):1851.
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© ARVO (1962-2015); The Authors (2016-present)
SENSIMED Triggerfish® can measure continuous 24 hours’ intraocular pressure (IOP) with a contact lens sensor. We evaluated fluctuations of IOP before and after selective laser trabeculoplasty (SLT) in normal tension glaucoma (NTG) patients
10 NTG patients were enrolled in this study (2 males and 8 females). The mean age of patients were 68.8±7.2 years old. All patients were treated with more than two glaucoma eye drops. All patients underwent SLT in 360 degrees. Changes in IOP were monitored with Triggerfish for 24 hours. We compared fluctuations of IOP before and 2 months after SLT with the range and mean deviations of IOP. Corneal thickness and curvature were obtained by anterior segment optical coherence tomography before and after 24-hour IOP measurement
The mean IOP was 13.0±2.7mmHg before SLT and decreased to 11.2±1.9 mmHg after 2 months of SLT (p=0.0098). The range of fluctuation of IOP was 490±103.2mVeq before SLT and 441.7±95.7mVeq after SLT (p=0.77). The mean deviation before SLT was 96.7±32.4mVeq and that after SLT was 109.6±40.7mVeq (p=0.625). Steeper meridian significantly decreased (p=0.0156) after wearing a contact lens of Triggerfish, while flatter meridian showed no significant difference (p=0.453). Corneal thickness showed no significant difference after wearing a contact lens.
SLT significantly decreased IOP, but it did not affect fluctuations of IOP in NTG patients. This is the first study to show changes in fluctuations of continuous IOP for 24hours before and after SLT in NTG patients.
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