June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Post-operative hemorrhage after vitrectomy for proliferative diabetic retinopathy with or without pre-surgical intravitreal bevacizumab
Author Affiliations & Notes
  • Sumihiro Kawano
    ophtalmology, kagoshima Univ Faculty of medicine, Kagoshima, Japan
  • Toshifumi Yamashita
    ophtalmology, kagoshima Univ Faculty of medicine, Kagoshima, Japan
  • Yasushi Sonoda
    ophtalmology, kagoshima Univ Faculty of medicine, Kagoshima, Japan
  • Keita Yamakiri
    ophtalmology, kagoshima Univ Faculty of medicine, Kagoshima, Japan
  • Taiji Sakamoto
    ophtalmology, kagoshima Univ Faculty of medicine, Kagoshima, Japan
  • Footnotes
    Commercial Relationships Sumihiro Kawano, None; Toshifumi Yamashita, None; Yasushi Sonoda, None; Keita Yamakiri, None; Taiji Sakamoto, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 216. doi:
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    • Get Citation

      Sumihiro Kawano, Toshifumi Yamashita, Yasushi Sonoda, Keita Yamakiri, Taiji Sakamoto; Post-operative hemorrhage after vitrectomy for proliferative diabetic retinopathy with or without pre-surgical intravitreal bevacizumab. Invest. Ophthalmol. Vis. Sci. 2013;54(15):216.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To evaluate the effect of pre-surgical intravitreal bevacizumab (IVB) on vitrectomy for proliferative diabetic retinopathy (PDR).

Methods: IVB was done for PDR eyes (12 consecutive eyes, IVB group) within one week prior to vitrectomy. Those received vitrectomy for PDR without IVB were used as a control (15 eyes, control group). Baseline characteristics of two groups, visual outcome, post-operative hemorrhage were investigated.

Results: There were no significant difference in the rate of increase of intraocular pressure (IVB group vs control group: 5 eyes VS 6 eyes, P=0.93), macular edema (IVB group vs control group: 11 eyes VS 13 eyes, P=0.69) and visual outcome (pre-operative logMAR: 1.46 VS 1.13 P=0.18, post-operative logMAR: 0.44 VS 0.52 P=0.62) between groups. Frequency of post-operative hemorrhage after 1 months were 4 times/15eyes, in IVB group and 0 times/12eyes in control group (P=0.057). No adverse events related to IVB such as stroke, hypertension, or unknown visual loss were observed during the observation.

Conclusions: Although the statistics did not reach significance, there was a tendency that pre-surgical IVB would decrease the incidence of hemorrhage after vitrectomy for PDR.

Keywords: 499 diabetic retinopathy • 561 injection • 762 vitreoretinal surgery  
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