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Nakashima Kei-Ichi, Toshihiro Inoue, Ayako Fukushima, Hirakawa Saori, Takahiro Kawaji, Hidenobu Tanihara; Evaluation of filtering blebs with transconjunctival oozing by anterior segment optical coherence tomography. Invest. Ophthalmol. Vis. Sci. 2013;54(15):2256.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate filtering blebs with transconjunctival oozing by anterior segment optical coherence tomography (AS-OCT).
Cross-sectional study. Forty-eight eyes of 48 patients with filtering blebs after trabeculectomy were examined at Kumamoto University Hospital between August 2011 and November 2012. Transconjunctival oozing was defined as transconjunctival aqueous egress on the bleb without point leak observed by slit-lamp, which was confirmed by digital pressure. Total bleb height, height of internal fluid-filled cavity, bleb wall thickness and bleb wall density were measured by three-dimensional AS-OCT. Age, glaucoma type, postoperative follow-up period, number of topical treatment, intraocular pressure (IOP), bleb vascularity grade classified by Moorfields Bleb Grading System, and bleb parameters of eyes with oozing were compared with eyes without oozing.
Twenty-five eyes (52.1%) of 48 eyes had oozing (25 eyes with digital ocular pressure and 2 eyes without). The average ages were 68.5 ± 10.8 years and 66.8 ± 9.8 years , follow-up periods were 549.3 ± 1192.0 days and 600.6 ± 829.0 days , IOPs were 11.2 ± 4.9 mmHg and 14.5 ± 4.2 mmHg , and bleb vascularity grades were 1.2 ± 0.4 and 2.2 ± 1.1 in eyes with oozing and without oozing, respectively. Total bleb heights were 1.08 ± 0.40 and 1.04 ± 0.53 mm, height of internal fluid-filled cavities were 0.37 ± 0.29 and 0.50 ± 0.53 mm , bleb wall thicknesses were 0.71 ± 0.35 and 0.54 ± 0.32 mm , and bleb wall densities were 125.10 ± 35.36 and 162.91 ± 41.33 optical density in eyes with oozing and without oozing, respectively. There were significant differences in IOPs (P = 0.0170), bleb vascularity (P <0.0001) and bleb wall densities (P = 0.0013) between the two groups, while there were no significant differences in other parameters.
Transconjunctival oozing was associated with IOP control and bleb wall properties.
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