June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
DETERMINATION OF OPTIC DISC HEMOGLOBIN QUANTITY IN OCULAR HYPERTENSION, COMPARED WITH OPTICAL COHERENCE TOMOGRAPHY
Author Affiliations & Notes
  • Paula Arribas Pardo
    Glaucoma. Instituto de Investigación Sanitaria San Carlos (IdISSC) Fundación de Investigación Biomédica del Hospital Clínico San Carlos, Madrid, Spain., Madrid, Spain
  • Julian Garcia-Feijoo
    Glaucoma. Instituto de Investigación Sanitaria San Carlos (IdISSC) Fundación de Investigación Biomédica del Hospital Clínico San Carlos, Madrid, Spain., Madrid, Spain
  • Manuel González-de-la-Rosa
    Hospital Universitario de Canarias., La Laguna, Spain
  • Ignacio Rodriguez-Uña
    Glaucoma. Instituto de Investigación Sanitaria San Carlos (IdISSC) Fundación de Investigación Biomédica del Hospital Clínico San Carlos, Madrid, Spain., Madrid, Spain
  • Clara Berrozpe Villabona
    Glaucoma. Instituto de Investigación Sanitaria San Carlos (IdISSC) Fundación de Investigación Biomédica del Hospital Clínico San Carlos, Madrid, Spain., Madrid, Spain
  • Federico Saenz-Frances
    Glaucoma. Instituto de Investigación Sanitaria San Carlos (IdISSC) Fundación de Investigación Biomédica del Hospital Clínico San Carlos, Madrid, Spain., Madrid, Spain
  • Jose Martinez de la Casa
    Glaucoma. Instituto de Investigación Sanitaria San Carlos (IdISSC) Fundación de Investigación Biomédica del Hospital Clínico San Carlos, Madrid, Spain., Madrid, Spain
  • Enrique Santos-Bueso
    Glaucoma. Instituto de Investigación Sanitaria San Carlos (IdISSC) Fundación de Investigación Biomédica del Hospital Clínico San Carlos, Madrid, Spain., Madrid, Spain
  • Carmen Mendez-Hernandez
    Glaucoma. Instituto de Investigación Sanitaria San Carlos (IdISSC) Fundación de Investigación Biomédica del Hospital Clínico San Carlos, Madrid, Spain., Madrid, Spain
  • Footnotes
    Commercial Relationships Paula Arribas Pardo, None; Julian Garcia-Feijoo, Trancend (C), Ivantis (C), Glaukos (C), MSD (C), Allergan (F), Pfizer (F), Alcon (C), Sensimed (F), Sylentis (F), Bausch and Lomb (C); Manuel González-de-la-Rosa, Haag Streit (P), Oculus (P); Ignacio Rodriguez-Uña, None; Clara Berrozpe Villabona, None; Federico Saenz-Frances, None; Jose Martinez de la Casa, None; Enrique Santos-Bueso, None; Carmen Mendez-Hernandez, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 2290. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Paula Arribas Pardo, Julian Garcia-Feijoo, Manuel González-de-la-Rosa, Ignacio Rodriguez-Uña, Clara Berrozpe Villabona, Federico Saenz-Frances, Jose Martinez de la Casa, Enrique Santos-Bueso, Carmen Mendez-Hernandez, PI09/90933 of the Instituto de Salud Carlos III grants. Red Temática de Investigación Cooperativa ISCIII: RD07/062; DETERMINATION OF OPTIC DISC HEMOGLOBIN QUANTITY IN OCULAR HYPERTENSION, COMPARED WITH OPTICAL COHERENCE TOMOGRAPHY. Invest. Ophthalmol. Vis. Sci. 2013;54(15):2290.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: To determine the diagnostic capacity of a new method for measuring hemoglobine (Hb) levels at the optic nerve head (ONH), Laguna ONhE (Optic Nerve Hemoglobine) compared with optical coherence tomography (OCT Spectralis) in ocular hypertension (OHT).

Methods: OHT eyes (n=40) and healthy eyes (n=44) underwent a transversal study using TOP G1 perimetry, OCT Spectralis and optic disc retinographies acquired with a non-mydriatic fundus camera (Canon non-mydriatic retinal camera CD-DGi, Canon Inc.,Tokyo, Japan). Laguna ONhE program was used to calculate the Hb amount of the ONH. Area under the receiver operating characteristic curves (AUC) and correlation between structural and functional parameters were determined (Spearman Rho).

Results: The greatest AUC corresponded to Laguna ONhE parameters GDF (Glaucoma Discrimination Function) (0.844 CI 95% 0.762- 0.926), Hemoglobin concentration in the vertical optic disc axis (8 & 20 Sector) (0.817 CI 95% 0.726- 0.907) and C/D Estimated Ratio (0.806 CI 95% 0.714- 0.898), versus the ones obtained for OCT Retinal Nerve Fiber Layer Thickness (RNFL) (0.577 CI 95% 0.439- 0.715).

Conclusions: Discrimination between OHT and controls is better made with Laguna ONhE program than OCT Spectralis in ocular hypertension eyes.

Keywords: 549 image processing • 610 nerve fiber layer • 628 optic flow  
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×