June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Perimetric results in patients with Multiple Sclerosis without optic neuritis
Author Affiliations & Notes
  • Katja Goebel
    Ophthalmology, Schloss Park Clinic, Berlin, Germany
  • Carl Erb
    Eye clinic, Wittenbergplatz, Berlin, Germany
  • Footnotes
    Commercial Relationships Katja Goebel, None; Carl Erb, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 2349. doi:
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      Katja Goebel, Carl Erb; Perimetric results in patients with Multiple Sclerosis without optic neuritis. Invest. Ophthalmol. Vis. Sci. 2013;54(15):2349.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: Aim of the study was to investigate the perimetric results in patients with Multiple Sclerosis without optic neuritis.

Methods: All patients and controls underwent ophthalmologic examinations (visual acuity, refraction, slit lamp and fundus examination, intraocular pressure) and were examined with the achromatic perimetry (Octopus 311, G1, Haag-Streit), frequency doubling perimetry (Matrix, 30-2, Zeiss Meditec) and flimmer perimetry (Pulsar, TOP/CP-T30W, Haag-Streit). The statistic analysis took place with the Wilcoxon - test (side comparison) and Mann- Whitney- U- test (group comparison).

Results: 26 patients with Multiple Sclerosis without optic neuritis (m : f=11 : 15, average age 43.8 ± 9.4 years) were included into the study and compared with age-corresponding controls (n=26, m:f=6:20, average age 40.0 ± 10.3years). The ophthalmologic examinations in all patients and controls showed no statistical differences. Regarding the perimetric results we found statistic significant differences between the two groups in the achromatic perimetry (Mean Deviation in dB: controls vs MS-patients: -0.38 ± 1.14 vs 1.2 ± 1.57, Loss Variance in dB: controls vs MS-patients: 3.58 ± 1.3 vs 7.6 ± 10.1), the frequency doubling perimetry (Mean Deviation in dB: controls vs MS-patients: 0.66 ± 1.52 vs -3.32 ± 2.89, Pattern Standard Deviation in dB: controls vs MS-patients: 2.55 ± 0.27 vs 3.1 ± 0.53) and flimmer perimetry (Mean Deviation in dB: controls vs MS-patients: 0.05 ± 0.9 vs 2.7 ± 3.13, corrected Loss Variance in dB: controls vs MS-patients: 2.1 ± 0.55 vs 3.0 ± 0.67).

Conclusions: In patients with Multiple Sclerosis without optic neuritis we found an in-fluence of the perimetric results.

Keywords: 758 visual fields • 613 neuro-ophthalmology: optic nerve  
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