June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Evaluation of Aqueous Flare values in Patients with Cystoid Macular Edema after Cataract Surgery
Author Affiliations & Notes
  • Lebriz Ersoy
    Department of Ophthalmology,, University of Cologne, Germany, Cologne, Germany
  • Albert Caramoy
    Department of Ophthalmology,, University of Cologne, Germany, Cologne, Germany
  • Tina Ristau
    Department of Ophthalmology,, University of Cologne, Germany, Cologne, Germany
  • Bernd Kirchhof
    Department of Ophthalmology,, University of Cologne, Germany, Cologne, Germany
  • Sascha Fauser
    Department of Ophthalmology,, University of Cologne, Germany, Cologne, Germany
  • Footnotes
    Commercial Relationships Lebriz Ersoy, None; Albert Caramoy, Bausch & Lomb (F), Fluoron GmbH (F), Alamedics GmbH&Co. KG (F); Tina Ristau, Novartis (F); Bernd Kirchhof, None; Sascha Fauser, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 258. doi:
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      Lebriz Ersoy, Albert Caramoy, Tina Ristau, Bernd Kirchhof, Sascha Fauser; Evaluation of Aqueous Flare values in Patients with Cystoid Macular Edema after Cataract Surgery. Invest. Ophthalmol. Vis. Sci. 2013;54(15):258.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To evaluate the role of aqueous flare in pseudophakic eyes with cystoid macular edema (CME) and its relationship to best corrected visual acuity (BCVA) and retinal thickness.

Methods: 30 pseudophakic eyes with clinically significant CME as well as 46 healthy pseudophakic eyes and 97 healthy phakic eyes as controls were enrolled in this study. BCVA, aqueous flare measurements with a laser flare-cell meter (Kowa FM-500, Kowa Co. Ltd, Tokyo, Japan) and spectral domain optical coherence tomography (SDOCT) volume scans were collected. Foveal central thickness (FCT) was assessed using custom software.

Results: Pseudophakic eyes with CME showed significantly higher flare values than healthy pseudophakic eyes (p<0.0001; median, 22.55 vs. 11.00 photon counts per millisecond (pc/ms)) and phakic eyes (p< 0.0001; median, 22.55 vs. 3.52 pc/ms). There was also a significant difference of flare values between pseudophakic and phakic healthy eyes (p<0.0001; median, 11.00 vs. 3.52 pc/ms). Among pseudophakic eyes, higher flare values correlated significantly with lower BCVA (p= 0.041). Higher flare values also correlated with higher FCT (p<0.0001) in the pseudophakic group.

Conclusions: Analysis of aqueous flare values revealed significant differences between eyes with clinically significant CME and healthy controls indicating higher inflammation levels in the anterior chamber of affected eyes.

Keywords: 585 macula/fovea • 557 inflammation  
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