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Seung Jae Lee, Ju Yong Seok, Haksu Kyung, Soo Young Lee; Case series of Macular Degeneration following Pars Plana Vitrectomy using Xenon Intraocular Endoillumination. Invest. Ophthalmol. Vis. Sci. 2013;54(15):2831.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate macular degeneration in various retinal diseases after vitrectomy with the use of Xenon intraocular endoillumination
The authors retrospectively analyzed clinical diagnosis, preoperative and postoperative visual acuity, timing of macular degeneration, fundus and optical coherence tomography (OCT) finding of 10 consecutive eyes with macular degeneration after vitrectomy with the use of Xenon intraocular endoillumination.
Diagnoses which macular degeneration occurred after vitrectomy with the use of Xenon intraocular endoillumination consisted of diabetic vitreous hemorrhage (3 eyes), rhegmatogenous retinal detachment (2 eyes), macular hole (2 eyes) and epiretinal membrane (3 eyes). In 5 eyes, macular degeneration involved the fovea. Postoperatively, macular degeneration occurred from 2 weeks to 34 months. Fundus findings showed retinal pigment epithelial pigmentary change and atrophy in all 10 eyes. Spectral Domain-OCT showed RPE clumping and disruption of photoreceptor IS/OS line. The mean central subfoveal thickness in 2 eyes with macular hole and 2 eyes with epiretinal membrane was 382μm before surgery and 232.25μm after surgery(p=0.028). The mean central subfoveal thickness in 3 eyes with diabetic vitreous hemorrhage and 2 eyes with rhegmatogenous retinal detachment decreased from 302μm to 223.8μm during follow-up period after surgery(p=0.100). In 7 eyes, central subfoveal thickness reduced below normal range. Postoperative BCVA was better than 20/60 in 5 eyes not involving fovea, but worse than 20/200 in 5 eyes involving fovea.
Macular degeneration after vitrectomy may be associated with the use of Xenon intraocular endoillumination toxicity. Therefore, when we select light source during intraocular surgery, care should be taken and we should minimize the occurrence of macular degeneration.
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