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na liao, Chaohong Li, Yiyu Li, Hao Chen, Qinmei Wang; Assessing retinal detailed structure in pathological myopia with adaptive optics scanning laser ophthalmoscope. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3433.
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© ARVO (1962-2015); The Authors (2016-present)
To examine the retinal detailed structure in pathological myopia with adaptive optics scanning laser ophthalmoscope (AOSLO).
The 20 eyes (10 emmetropias and 10 pathological myopias) of 20 subjects, whose ages ranged from 18 to 30, were enrolled. An AOSLO was used to obtain high resolution images of the macular photoreceptor mosaic, the surface-level pores of the lamina cribrosa and parafoveal capillary network of all participants.
AOSLO can compensate living human eye’s optical aberrations and get the retinal detailed histological image. Compared with the emmetropic eyes, the pathological myopia subjects showed an average lower cone packing densities in macular, greater lamina cribrosa pore areas, bigger foveal avascular zone (FAZ) and lower leukocyte speed.
AOSLO as a non-invasive technique is able to visualize detail images in vivo retina which can assist in detecting pathologic features and illuminating the reasons of the increased glaucoma susceptibility in highly myopic eyes. This novel technique provides opportunities to enhance the understanding of retinal pathogenesis.
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