June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Evaluation Of The Interface Between Keratoprosthesis and Donor Cornea By Anterior Segment OCT
Author Affiliations & Notes
  • Riccardo Scotto
    Ophthalmology, DiNOGMI, University of Genoa, Genova, Italy
  • Marina Papadia
    Ophthalmology, DiNOGMI, University of Genoa, Genova, Italy
  • Alessandro Bagnis
    Ophthalmology, DiNOGMI, University of Genoa, Genova, Italy
  • Carlo Enrico Traverso
    Ophthalmology, DiNOGMI, University of Genoa, Genova, Italy
  • Footnotes
    Commercial Relationships Riccardo Scotto, None; Marina Papadia, None; Alessandro Bagnis, None; Carlo Enrico Traverso, MSD (F), Alcon (F), Santen (F), Thea (F), Allergan (F)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 3476. doi:
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    • Get Citation

      Riccardo Scotto, Marina Papadia, Alessandro Bagnis, Carlo Enrico Traverso; Evaluation Of The Interface Between Keratoprosthesis and Donor Cornea By Anterior Segment OCT. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3476.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: The synthetic Keratoprosthesis can restore visual function in patients affected by corneal blindness that are poor candidates for keratoplasty. Advances in medical treatment have resulted in a marked improvement in retention rates and visual outcomes. Anterior Segment (AS) OCT imaging provides additional information about the status of the prosthesis and the donor graft cornea.

Methods: AS-OCT imaging was performed at every follow-up visit to analyze prosthesis structure, iris position and interface between device and donor cornea.

Results: Five eyes of 5 patients implanted with the Boston type I keratoprosthesis, between 2008 and 2011, were included in this retrospective analysis. Mean corneal thickness near the prosthesis was 626 ±34 μm (range 549-694 μm) in the nasal sector, and 643 ±59 μm in the temporal sector (range 571-657 μm).

Conclusions: Spectral-domain AS-OCT allows high resolution imaging of the keratoprosthesis device-donor cornea interface, precise visualization of the iris profile and quantification of the irido-corneal angle. This imaging technique, able to provide high-resolution images of the anterior segment, can help identify the risk for keratoprosthesis-related complications, such as corneal melting and angle closure glaucoma.

Keywords: 575 keratoprostheses • 421 anterior segment • 552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)  
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