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Alain Bron, Anna Francoz, Caroline Fiet, Christine Binquet, Claire Bonython-Kopp, Christophe Tzourio, Niyazi Acar, Lionel Bretillon, Catherine Creuzot-Garcher; Intraocular pressure and central corneal thickness in an old French population: The MONRACHET study. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3505.
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To describe the distribution of intraocular pressure (IOP) and central corneal thickness (CCT) in an old French population.
About 9000 individuals 65 years and older were included in the 3C cohort study since 1999 in 3 French cities (Bordeaux, Dijon and Montpellier). In Dijon, an additional ophthalmic examination was performed 10 years after the initial inclusions to assess the relation between systemic age-related diseases and eye diseases in the MONTRACHET Study (Maculopathy Optic Nerve nuTRition neurovAsCular and HEarT diseases). In this population-based study a thorough eye examination and a questionnaire were undertaken in each participant. Intraocular pressure (IOP) was measured with a noncontact pneumotonometer and central corneal thickness (CCT) was measured with an ultrasound pachymeter.
Among the 1035 participants of the MONTRACHET study only those without an ocular hypotensive treatment and those without evidence of glaucoma based on optic disc photographs were considered. Among these 911 individuals, 579 (64%) were female, 478 where phakic and the age was 82.2 ± 3.8 years. IOP in the right eye and the left eye was 14.6 ± 3.2 and 14.8 ± 3.2 mmHg, respectively, p = 0. 06. IOP decreased with age, (p < 0.01) and was similar in males and females (p = 0.07). IOP was lower in pseudophakic than in phakic participants 15.2 ± 3.2 and 15.4 ± 3.1 mmHg vs 13.9 ± 3.0 and 14.1 ± 3.1 mmHg for the right and the left eye, respectively, p < 0.01.CCT in the right eye and the left eye was 553.4 ± 34.4 μm and 555.7 ± 34.7 μm, respectively, p < 0.01. CCT was not influenced by the lens status and the refraction error. CCT was correlated to the age and the IOP, p < 0.01.
Few population-based studies focused on very old Caucasian subjects are available. These preliminary results of the MONTRACHET study give some specific aspects of IOP and CCT in elderly.
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