June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Cuantitative study of the trabecular meshwork and its relationship to the morphometry of the eye in the normal population using an anterior segment Fourier Domain OCT
Author Affiliations & Notes
  • José Fernández-Vigo López
    Ophthalmology, CIOA - UNIVERSIDAD DE EXTREMADURA, Madrid, Spain
  • José Ignacio Fernández-Vigo
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • CRISTINA FERNANDEZ-VIGO ESCRIBANO
    Centro de Oftalmologia Barraquer, Barcelona, Spain
  • Jose Martinez de la Casa
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • Julian Garcia-Feijoo
    Ophthalmology, Hospital Clinico San Carlos, Madrid, Spain
  • Footnotes
    Commercial Relationships José Fernández-Vigo López, None; José Ignacio Fernández-Vigo, None; CRISTINA FERNANDEZ-VIGO ESCRIBANO, None; Jose Martinez de la Casa, None; Julian Garcia-Feijoo, Trancend (C), Ivantis (C), Glaukos (C), MSD (C), Allergan (F), Pfizer (F), Alcon (C), Sensimed (F), Sylentis (F), Bausch and Lomb (C)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 3559. doi:
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      José Fernández-Vigo López, José Ignacio Fernández-Vigo, CRISTINA FERNANDEZ-VIGO ESCRIBANO, Jose Martinez de la Casa, Julian Garcia-Feijoo, ; Cuantitative study of the trabecular meshwork and its relationship to the morphometry of the eye in the normal population using an anterior segment Fourier Domain OCT. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3559.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To study the size of the trabecular meshwork (TM) with anterior segment Fourier Domain OCT, and analyze its relationship with the morphometric variables of the eye in a normal population.

Methods: Prospective study of one eye from 320 consecutive healthy patients. We examined the patients with Pentacam ®, IOL Master ®, and anterior segment RTVue ® (Optovue, California, USA) Fourier Domain OCT (AS-OCT). Images were obtained under standard light conditions, and when the signal strength intensity was greater than 30. Parameters evaluated included: age, sex, IOP, refractive error, axial length, pupil diameter and pachymetry. Anterior chamber (AC) parameters examined: depth, volume and diameter. Angle parameters examined: nasal and temporal width measured in degrees, angle opening distance (AOD), trabecular iris space area (TISA) and iris thickness; length, thickness and area of the trabecular meshwork (TM). Pearson correlation analysis was performed to study the correlation between the TM size and the rest of the variables.

Results: 37 patients (11.7%) were excluded because the TM could not be identified due to low image quality. The mean values of the population were: age: 45 ± 14.2 years (range 19 to 84), IOP: 15.92 ± 3.8 mmHg (range 8 to 26.4), sphere: -0.4 ± 2.79 diopters (range -6.25 to 6.5), axial length: 23.91 ± 1.51mm (range 20.03 to 29.14), AC depth: 3.42 ± 0.43 mm (range 2.45 to 4.38), AC diameter: 11.93 ± 0.39 mm (range 11 to 13), iris thickness: 412.6 ± 88.88 microns (range 195 to 910), pupil diameter 2.96 ± 0.62 (1.71 to 5.51), pachymetry: 549.01 ± 32.96 microns(range 471 to 643). The mean temporal angle width was 38.8 ± 12.7 degrees (range 14.5 to 78.2), AOD: 587.18 ± 261.65 microns, (range 64 to 1440), TISA: 0.201 ±0.093 mm2 (range 0.027 to 0.519). The mean area of TM was 0.067 ± 0.023 mm2 (range 0.023 to 0.126), with an average length of 536 ± 130 microns (range 271 to 879) and an average thickness of 170 ± 33 microns (range 83 to 267). There was no significant correlation between the TM size and any of the variables studied (r <0.13). Cited correlations were statistically significant (p <0.05%).

Conclusions: SA Fourier Domain OCT enabled us to analyze and measure the MT in 88.3% of eyes. Our results suggest that the TM size is not related with any ocular or general parameter studied.

Keywords: 735 trabecular meshwork • 420 anterior chamber • 552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)  
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