June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
An Investigation into Declared vs Actual Content of Commercially Available Food Supplements Containing the Macular Carotenoids
Author Affiliations & Notes
  • Sakina Kashani
    Macular Pigment Research Group, Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
  • Katherine Meagher
    Macular Pigment Research Group, Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
  • Stephen Beatty
    Macular Pigment Research Group, Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
  • David Thurnham
    Northern Ireland Centre for Food and Health (NICHE), University of Ulster, Coleraine, United Kingdom
  • Alan Howard
    Howard Foundation, Cambridge University, Cambridge, United Kingdom
  • John Nolan
    Macular Pigment Research Group, Chemical and Life Sciences, Waterford Institute of Technology, Waterford, Ireland
  • Footnotes
    Commercial Relationships Sakina Kashani, None; Katherine Meagher, None; Stephen Beatty, None; David Thurnham, Howard Foundation, Cambridge UK (C); Alan Howard, None; John Nolan, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 3772. doi:
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    • Get Citation

      Sakina Kashani, Katherine Meagher, Stephen Beatty, David Thurnham, Alan Howard, John Nolan; An Investigation into Declared vs Actual Content of Commercially Available Food Supplements Containing the Macular Carotenoids. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3772.

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      © ARVO (1962-2015); The Authors (2016-present)

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  • Supplements
Abstract
 
Purpose
 

The macular carotenoids lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ) are commercially available in a variety of food supplements. These supplements are promoted to support eye health and wellbeing. The purpose of this study is to analyse these supplements in order to test concordance between declared and actual content of the respective macular carotenoids.

 
Methods
 

20 commercially available food supplements claiming content of L, and/or Z, and/or MZ (some with co-antioxidants) were selected for carotenoid analysis by high performance liquid chromatography (HPLC). 3 capsules/tablets were selected at random from each packet.

 
Results
 

Table 1 presents the declared vs (average) measured macular carotenoid content of seven supplements tested.

 
Conclusions
 

The observed discrepancies between actual and alleged concentrations of the respective macular carotenoids, and the identification of the presence of MZ in commercially available preparations is particularly important when such formulations are used for research.

  
Keywords: 444 carotenoids/carotenoid binding proteins • 587 macular pigment • 424 antioxidants  
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