Purchase this article with an account.
Pukhraj Rishi, Carol Shields, Kaitlin Patrick, Mohammed Khan, Jerry Shields; Pain as presenting feature of uveal melanoma. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4248.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To describe the clinical features and outcomes of patients with pain from underlying uveal melanoma.
Retrospective case series of 9 patients.
The mean patient age at presentation was 62 years (median 62 years, range 41-83 years). The pain manifested in the periocular region (n=9) and additionally as diffuse ipsilateral headache (n=5). On a scale of 0-10, the average pain score was 7.5 (median 9, range 2-10) and four patients reported pain severity at maximum (10/10). The average duration of pain was 27 days (median 7, range 2-180 days). Visual acuity was reduced in 8 of 9 eyes. The melanoma was located in the ciliary body (n=3) or choroid (n=6). The mean tumor basal diameter was 18 mm (median 18 mm, range 14-24 mm) and mean tumor thickness was 7 mm (median 6 mm, range 5-11 mm). Clinical features of spontaneous melanoma regression was evident in all cases (n=9). Treatment included plaque radiotherapy (n=5), enucleation (n=3) and one patient refused therapy (n=1). Following therapy, all patients were relieved of pain.
Ocular pain or headache can be the initial manifestation of uveal melanoma. Following ocular therapy, pain symptoms are relieved.
This PDF is available to Subscribers Only