June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Analysis of the Correlation Between Peripapillary Choroidal Thickness and the Nerve Fiber Layer Damage in Primary Open Angle Glaucoma Patients
Author Affiliations & Notes
  • Nimesh Patel
    Tufts University School of Medicine, Boston, MA
  • Chandrasekharan Krishnan
    Tufts University School of Medicine, Boston, MA
    New England Eye Care Center, Boston, MA
  • Footnotes
    Commercial Relationships Nimesh Patel, Research to Prevent Blindness (F); Chandrasekharan Krishnan, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 4452. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Nimesh Patel, Chandrasekharan Krishnan; Analysis of the Correlation Between Peripapillary Choroidal Thickness and the Nerve Fiber Layer Damage in Primary Open Angle Glaucoma Patients. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4452.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: To examine the relationship between peripapillary choroidal thickness, nerve fiber layer thickness and visual field loss in asymmetric Primary Open Angle Glaucoma patients.

Methods: 124 eyes of 62 Primary Open Angle Glaucoma (POAG) patients seen at New England Eye Center between September 2009 and August 2011 were analyzed. Nerve fiber layer thickness measurements were obtained via Cirrus OCT (Carl Zeiss Meditec, Inc). Humphrey visual fields (Carl Zeiss Meditec, Inc) were performed and Mean Deviation data was used for analysis. Peripapillary choroidal thickness measurements were obtained via Cirrus OCT high definition raster scanning in four quadrants (superior, inferior, temporal and nasal) at distances 500µm, 1000µm and 1500µm from the optic nerve. A single sub-foveal.measurement was also obtained. Interocular differences (OD-OS) in choroidal thickness were then compared to interocular differences in nerve fiber layer thickness and visual field mean deviation to see whether these variables were correlated.

Results: There was no statistically significant correlation (Pearson’s correlation coefficient, Sig 2-tailed value) found in regards to interocular differences in peripapillary choroidal thickness and interocular differences in nerve fiber layer thickness or mean deviation in visual field in any of the four quadrants or in the subfoveal region (sig two-tailed <0.05) in this group of POAG patients.

Conclusions: Based on the results of this study, changes in peripapillary choroidal thickness do not seem to correlate with nerve fiber layer thickness or with visual field damage in patients with primary open angle glaucoma.

Keywords: 452 choroid • 568 intraocular pressure • 610 nerve fiber layer  
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×