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Shlomo Melamed, Modi Goldenfeld, Daniel Cotlear, Alon Skaat; High Intensity Focused Ultrasound (HIFU) in patients with Refractory Glaucoma. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4744.
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To evaluate Efficacy and Safety of High Intensity Focused Ultrasound (HIFU) in patients with Refractory Glaucoma.
Our study is a prospective study of 20 eyes of 20 patients with Refractory Glaucoma. HIFU is a new technology for Cyclophotocoagulation, utilizing a novel miniature probe with 6 piezoceramic transducers emitting ultrasound energy focused on the ciliary body and processes. All patients had an IOP of at least 30 mm Hg with maximally tolerated medical treatment and at least one invasive glaucoma surgery. All eyes were treated with HIFU delivered through 6 high-frequency transducers operating at 21 MHz and emitting for 6 seconds each. Complete Ophthalmic examination was performed before Rx and at 1 day, 1 week , 1, 3 and 6 months.
Intraocular pressure was reduced by 42.6 % (P < 0.01) from a mean preoperative value of 36.4 ± 2.8 mm Hg to a mean postoperative value of 27.8 ± 4.3, 18.6 ± 3.6 and 20.9 ± 5.3 mm Hg at 1 day, 1 week and 3 months , respectively. No major intraoperative or postoperative complications were observed.
HIFU is a very safe and effective novel methodology for reducing IOP in Refractory Glaucoma cases.
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