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MASAHIRO MAEDA, Natsu Kondo, Kazunori Onuki, Asato Hasegawa, Trabectome study group; Comparison of the outcomes of Trabectome with Trabeculotomy with deep Sclerectomy - Ab Interno vs Ab Externo approach. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4757.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the outcomes of Trabectome and Trabeculotomy with deep Sclerectomy in Japanese patients.
This study is retrospective, non-randomized matched pair study. 20 eyes which had undergone trabeculotomy with deep Sclerectomy (TDS) were included in the study. 20 eyes from the Trabectome database were selected as the study group. Matching criteria included age, combined surgery performed such as phacoemulsification and type of glaucoma. The outcome measures recorded are intraocular pressure (IOP), glaucoma medications before and after surgery and the occurrence of post-operative secondary surgeries if any.
At 12 months, mean pre-operative IOP and glaucoma medications were reduced from 27.5 ± 10.6 mmHg and 2.8 ± 1.0 to 15.7 ± 2.8 mmHg (p<0.01) and 1.3 ± 1.3 (p<0.01) respectively in Trabectome group. No patient required subsequent glaucoma surgeries. In TDS group, mean pre-operative IOP and glaucoma medications were reduced from 26.4 ± 7.9 mmHg and 3.1 ± 1.2 to 13.5 ± 3.7mmHg (p<0.01) and 2.1± 1.0 (p<0.01) respectively at 12 months. One patient was required to undergo another trabeculectomy. There was no statistical significant difference between both groups in IOP (p=0.06) and medications (p=1.0) at 12 months.
Both TDS and Trabectome successfully lower IOP and the need for glaucoma medications. Trabectome is a viable alternative to TDS in Adult Japanese patients.
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