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Alan Tomlinson, Raied Fagehi, Velitchko Manahilov; Effect of care solutions on contact lens in-vivo wettability at insertion and end of day. Invest. Ophthalmol. Vis. Sci. 2013;54(15):492.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the wetting of a soft contact lens (SCL) after storage in various multipurpose solutions (MPS) (compared to wetting with the pack solution), to assess the sustained benefits after 8 hours of wear.
Ten SCL wearers (age range 26.6± 6.3 yrs) were included in this study. A Doane interferometer captured images of the pre-lens tear film on a single type of SCL, ACUVUE OASYS (Johnson & Johnson). The SCL wettability was measured after storage in the pack solution or one of five MPS: Opti-Free EverMoist and Express (Alcon), COMPLETE MPS (AMO), ReNu and Biotrue (Bausch & Lomb). The wettability was measured after 15 min (time A) and 8 hours (time B) of wear of the lens by each subject. Four previously described parameters of wettability were assessed: onset latency (OL), the time to first break-up; drying duration (DD), the duration of drying after first break-up; the maximum speed of drying (MS); and the time to reach this maximum speed (PL).* The OSDI questionnaire was completed by the subjects, at each visit, to evaluate the subjective response to the solutions.
There was no significant difference between CL wetting measured after storage in the MPS compared to the pack solution for all four wetting variables (Friedman test, P>0.05). However, storage of the lens in some MPSs showed more sustained wetting after 8 hours wear, with similar values at (A) and (B); for OL, ReNu and Complete; for DD and MS Biotrue, Express and Complete; and for PL ReNu, Express and Complete. The OSDI questionnaire showed less discomfort after 8 hours wear (at B) with storage in all the MPSs compared to the pack solution (p< 0.02).
The effect of all MPS on the initial wetting of a SCL (compared to that with the pack solution) was limited. However, the ability to sustain wetting of a SCL over 8 hours of wear was better with Biotrue, Opti-Free Express and Complete. The wetting parameter of drying duration gave the closest objective measure to subjective responses to lens wear (Figure 1and 2). *Fagehi R, Tomlinson A, Manahilov V. ARVO 2011 E-abstract: 6524, 2011.
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