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Jennifer Jung, Ashley Laing, Emily McCourt, Rebecca Braverman; Analysis of electroretinograms performed from 2009 to 2011 at Children's Hospital Colorado. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5119.
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© ARVO (1962-2015); The Authors (2016-present)
To review the use of electroretinograms at a tertiary pediatric hospital. To identify the common indications for referral and usefulness in diagnosis.
Retrospective chart review of electroretinograms performed at Children’s Hospital of Colorado from 2009 to 2011. One hundred and nineteen patients (male 60, female 59) aged <18 years were included, and 154 electroretinograms were reviewed.
The average age at the time of first electroretingram was 4.95 years (range 3 months to 18 years). The most common reasons for referral were nystagmus (n = 37), decreased vision (n= 29) and vigabatrin (n=26). Most common electroretinography diagnosis was rod-cone dystrophy. The first electroretinogram for each patient confirmed the clinical suspicion in 63.4% (n=59) of cases, excluding vigabatrin patients. With subsequent genetic testing, specific diagnosis resulted in 15% (n=14) of cases. There were only three normal electroretinogram results based on normative value set by the manufacturer of the instrumentation used.
Electroretinograms can be a valuable tool in evaluating pediatric eye disease, especially when combined with clinical correlation. However, the lack of normative data for children may affect the accuracy of interpretation.
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