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RUTH GEORGINA NAVARRETE ORTEGA, RUTH GEORGINA NAVARRETE ORTEGA, Hector Perez Grovas; Hemofiltration impact on intraocular pressure in patients with end stage renal disease without any evidence of glaucoma. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5661.
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PURPOSE: To determinate the intraocular pressure (IOP) changes in patients with renal replacement therapy by hemofiltration.
METHODS: 15 patients of 32.5±12 years, with more than 2 months in hemofiltration, steady, whithout any antihypertensives drugs, and no primary open glaucoma precedent. Tonopen readings of IOP where obtained sequentially 30 minutes before hemofiltration treatment, at 60, 90, 120 and 240 minutes during the procedure and 30 minutes after the treatment. The hemofiltration prescription was with an ordinary FMC-4008H machine, polisulfona F80 filter, and 4 hours long.
RESULTS: The mean basal intraocular pressure was 17.3±4 mmHg for the right eye and 17.0±4 mmHg for the left eye. According to the Tonopen readings of IOP during the treatment it was found for the right eye 16.7±5mmHg at 60 minutes, 17.7±5 mmHg at 90 minutes, 17.1±4mmHg at 120 minutes, 16.6±4mmHg at 240 minutes and 14.6±4* mmHg after hemofiltration. And for the left eye were 16.9±4 at 60 minutes, 19.2±3, at 90 minutes, 17.1±3 at 120 minutes,17.4±4 at 240 minutes and 15.1±4* after hemofiltration treatment. Statistical ANOVA was used. There were no statistical significant changes of intraocular pressure during the treatment. Indeed at the end of the treatment it was found a statistical significant decrease of IOP (p 0.005), in contrast with the other time of measure.
CONCLUSIONS: Hemofiltration treatment decreased IOP after 30 minutes of renal replacement therapy.
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