June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Curry consumption and high myopia in adults: A possible protective effect
Author Affiliations & Notes
  • Ainur Anuar
    Epidemiology, Singapore Eye Research Institute, Singapore, Singapore
    Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • Yingfeng Zheng
    Epidemiology, Singapore Eye Research Institute, Singapore, Singapore
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangzhou, China
  • Lei Huang
    Epidemiology, Singapore Eye Research Institute, Singapore, Singapore
  • Baskaran Mani
    Epidemiology, Singapore Eye Research Institute, Singapore, Singapore
  • Carol Cheung
    Epidemiology, Singapore Eye Research Institute, Singapore, Singapore
  • Ching-Yu Cheng
    Epidemiology, Singapore Eye Research Institute, Singapore, Singapore
  • Merwyn Chew
    Epidemiology, Singapore Eye Research Institute, Singapore, Singapore
  • Jodhbir Mehta
    Epidemiology, Singapore Eye Research Institute, Singapore, Singapore
    Duke-NUS Graduate Medical School of Medicine, National University of Singapore, Singapore, Singapore
  • Tien Wong
    Epidemiology, Singapore Eye Research Institute, Singapore, Singapore
    Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
  • Tin Aung
    Epidemiology, Singapore Eye Research Institute, Singapore, Singapore
    Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
  • Footnotes
    Commercial Relationships Ainur Anuar, None; Yingfeng Zheng, None; Lei Huang, None; Baskaran Mani, None; Carol Cheung, None; Ching-Yu Cheng, None; Merwyn Chew, None; Jodhbir Mehta, None; Tien Wong, Allergan (C), Bayer (C), Novartis (C), Pfizer (C), GSK (F), Roche (F); Tin Aung, Alcon (R), Alcon (C), Alcon (F), Allergan (R), Allergan (C), Carl Zeiss Meditec (F), Carl Zeiss Meditec (R), Ellex (F), Ellex (R), Santen (R)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 5705. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Ainur Anuar, Yingfeng Zheng, Lei Huang, Baskaran Mani, Carol Cheung, Ching-Yu Cheng, Merwyn Chew, Jodhbir Mehta, Tien Wong, Tin Aung, ; Curry consumption and high myopia in adults: A possible protective effect. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5705.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: To study the effects of curry consumption on the risk of myopia and high myopia in adults.

Methods: Time outdoors has been shown to reduce the risk of myopia, suggesting a possible relationship with vitamin D. A popular spice in Middle Eastern and Asian countries, curcumin, the principle ingredient in curry, is a potent nutritionally derived ligand to the human vitamin D receptor (VDR), its coupling exerting bioeffects. In this cross-sectional, population based study of Singaporean adults of Indian ethnicity, the dietary effects of curry consumption on the risk of adult myopia and high myopia was investigated. From 3400 subjects who underwent a standardized interview, ocular examinations, and ocular biometry, 741 subjects (without prior cataract surgery) were included. Diet was assessed using a semi-quantitative food-frequency questionnaire. Frequency of curry consumption was categorized into: frequent (daily), occasional (at least once a week to once a month) and rarely or never (less than once a month or never). Refractive error was determined via autorefraction, followed by subjective refraction. Emmetropia was defined as spherical equivalent (SE) of -0.5 to +0.5 D dioptre (D), hyperopia as > +0.5 D, myopia as < -0.5 D but not less than -6.0 D, and high myopia < - 6.0 D. Axial length (AL) was determined by partial laser interferometry. As the Spearman correlation coefficient for SE in the left and right eye was high, only right eyes were analyzed.

Results: Out of 741 subjects, 656 reported frequent consumption, 31 occasional, and 54 rarely consumed curry. In univariate analysis, except for education level (P<0.0001), neither axial length, height, presence of cataract, nor the amount of time spent reading and writing were found to be significantly associated with the frequency of curry consumption. Using emmetropes as reference, and adjusting for age, gender, and education level, the odds of high myopia were low and significant in subjects who consumed curry daily (frequent) : odds ratio (OR) of 0.25 , 95% Confidence Interval (95% CI) 0.08 to 0.83, P = 0.023. Curry consumption was however not protective against myopia of less than -6.0 D.

Conclusions: Frequent (daily) consumption of curry may be protective against high myopia in adults.

Keywords: 605 myopia • 464 clinical (human) or epidemiologic studies: risk factor assessment  
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×