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Sarah Wehrli, Marilyn Mets, Iris Kassem, Amani Fawzi, Nathalie Azar, Irene Maumenee; Biometric characteristics of the Marfan eye: From the Marfan Eye Consortium of Chicago. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5709.
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© ARVO (1962-2015); The Authors (2016-present)
To describe the ocular biometry in a group of 60 individuals with Marfan syndrome.
Seventy two patients were seen on August 2nd as a part of the National Marfan Foundation 2012 Annual Conference. Of those, 60 consented to the study and underwent an ophthalmologic examination including measurement of axial length (AL), anterior chamber depth (ACD), lens thickness (LT), pachymetry and keratometry using ultrasonic contact A scan, IOL master, Sonomed pachymetry and Marco keratometer. Lens status and current spectacle refraction were also recorded and spherical equivalent (SE) was calculated. Data from the subjects’ right eye only were included in these analyses.
Biometric and refractive data were analyzed on 60 patients, ages 23 months to 56 years, 25 of whom were male. Subjects were analyzed in two separate groups according to age, group one less than 18 years and group two greater than 18 years. Group one average measurements were AL 23.62mm (SD=4.07), ACD 3.63mm (SD=0.59), LT 3.74mm (SD=0.18), pachymetry 544.27um (SD=46.91), corneal power 41.61D (SD=2.39) and SE -5.83D (SD=6.16). In subjects 18 years and older, average measurements were AL 25.39mm (SD=1.91), ACD 3.6mm (SD=0.61), LT 3.84mm (SD=0.48), pachymetry 542.24um (SD=42.25), corneal power 41.58D (SD=2.09) and SE -4.71D (SD=5.88). We were unable to obtain all measurements from all patients because many of the subjects were young children at the time of the examination.
This study provides a baseline of biometric data for patients with Marfan syndrome. The biometric and refractive data collected from this group of individuals will hopefully be used to identify possible biometric risk factors for the development of retinal detachment.
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