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Yasushi Ikuno, Xinxiao Gao, Satoko Fujimoto, Kohji Nishida; Risk factors for development of full thickness macular holes following pars plana vitrectomy for myopic foveoschisis. Invest. Ophthalmol. Vis. Sci. 2013;54(15):5782.
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© ARVO (1962-2015); The Authors (2016-present)
To explore the risk factors of secondary full thickness macular holes following pars plana vitrectomy with inner limiting membrane (ILM) peeling for myopic foveoschisis
The medical records of all patients who underwent pars plana vitrectomy with ILM peeling for myopic foveoschisis with or without retinal detachment from January 2002 to June 2012 were retrospectively reviewed. The factors for developing of postoperative full thickness macular holes were investigated.
Forty-two eyes with myopic foveoschisis but without macular hole before surgery were included in this study and 8 cases (19.0%) of them were identified to develop a postoperative full thickness macular hole by optical coherence tomography (OCT) during the follow-up period. No significant association of age (P =.369), axial length (P =.113), visual acuity (P =.859), status of fovea (P =.331), posterior staphyloma (P =1.000) or chorioretinal atrophy (P =0.837) were found between patients with and without secondary macular holes. Among the characteristics on OCT images, the percentage of eyes with the inner segment/outer segment junction (IS/OS) defect was significantly higher in the patients with macular hole than in those without macular hole (P =.013, Fisher exact test). IS/OS defect (P =0.018) was the only significant risk factor for development of secondary macular holes by logistic regression analysis.
Development of secondary macular holes may occur in myopic foveoschisis following pars plana vitrectomy with ILM peeling. Preoperative IS/OS defect can be a risk factor.
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