June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Symptoms and Findings in a Norwegian Cohort of Patients with Meibomian Gland Dysfunction
Author Affiliations & Notes
  • Ola Rygh
    Torreoyneklinikken AS, Oslo, Norway
    Eye department, Hospital of Vestfold, Tonsberg, Norway
  • Jon Roger Eidet
    Torreoyneklinikken AS, Oslo, Norway
    Synslaser Kirurgi, Oslo, Norway
  • Xiangjun Chen
    Torreoyneklinikken AS, Oslo, Norway
    Synslaser Kirurgi, Oslo, Norway
  • Tor Utheim
    Torreoyneklinikken AS, Oslo, Norway
    Department of Medical Biochemistry, Oslo University Hospital Ulleval, University of Oslo, Oslo, Norway
  • Andreas Thyholdt
    dbConsult, Tromso, Norway
  • Oeygunn Aass Utheim
    Torreoyneklinikken AS, Oslo, Norway
    Department of Medical Biochemistry, Oslo University Hospital Ulleval, University of Oslo, Oslo, Norway
  • Filip Stojanovic
    Torreoyneklinikken AS, Oslo, Norway
    Synslaser Kirurgi, Oslo, Norway
  • Aleksandar Stojanovic
    Torreoyneklinikken AS, Oslo, Norway
    Synslaser Kirurgi, Oslo, Norway
  • Sten Raeder
    Torreoyneklinikken AS, Oslo, Norway
    Department of Clinical Medicine, University of Bergen, Bergen, Norway
  • Footnotes
    Commercial Relationships Ola Rygh, None; Jon Roger Eidet, None; Xiangjun Chen, None; Tor Utheim, None; Andreas Thyholdt, None; Oeygunn Aass Utheim, None; Filip Stojanovic, None; Aleksandar Stojanovic, None; Sten Raeder, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 6009. doi:
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      Ola Rygh, Jon Roger Eidet, Xiangjun Chen, Tor Utheim, Andreas Thyholdt, Oeygunn Aass Utheim, Filip Stojanovic, Aleksandar Stojanovic, Sten Raeder; Symptoms and Findings in a Norwegian Cohort of Patients with Meibomian Gland Dysfunction. Invest. Ophthalmol. Vis. Sci. 2013;54(15):6009.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To present the first data (64 patients) from a Norwegian cohort of patients with Meibomian gland dysfunction at the Dry Eye Clinic in Norway.

Methods: Anamnestic information was obtained by using McMonnies questionnaire (15 questions), the Ocular Surface Disease Index (12 questions), and the American-European Consensus Criteria for Sjogren syndrome (6 questions). Data from 64 consecutive patients with MGD and preexisting dry eye symptoms were included. The patients underwent a 40 minute examination with an extensive panel of dry eye related analyses. The analyses were performed by a single clinician to ensure a standardized investigation method.

Results: The mean age of the population was 55 years and 64 % were women. Five percent of the patients were contact lens users. Mean McMonnies Dry Eye Index Score was 14, the Ocular Surface Disease Index (OSDI) was 16 and the Mean Dry Eye Severity Level (DESL) was 2.1 (range, 0-3). Eighty-five percent reported dryness, 75% soreness, 56% itching, 75% grittiness and 27% burning sensation in their eyes. Light sensitivity was mentioned by 73% of the patients, while 36 % reported mouth dryness. Thirtynine percent had a tear meniscus height <100 microns. Mean osmolarity was 305.4 mOsms/L (range, 292-329), mean blink rate 20 (range, 4-48), mean blink interval 7,1 (1.4-15), mean corneal sensibility 58.3 (range, 45-60) (using Cochet-Bonnet aesthesiometer), mean FBUT 6.0 (range, 1-14), mean Ocular Protection Index (OPI) 2.0 (range, 0.4-7.1), mean vital staining score 2.0 (range, 0-12) (using lissamine green and Oxford schema), mean Schirmer I 16.7 (range, 1-35), mean meibum quality 4.0 (range, 0-17), mean meibum expressibility 1.0 (range, 0-2), and mean intraocular pressure 14.0 (range, 7-23).

Conclusions: Most of the patients presented a low degree of Meibomian glad dysfunction and a corresponding low degree of osmolarity. Schirmer I had the widest range of measurements in this patient group.

Keywords: 486 cornea: tears/tear film/dry eye  
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