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Dordi Austeng, Ramiro Maldonado, Sharon Freedman, David Wallace, Cynthia Toth, ; New onset macular edema after laser photocoagulation for retinopathy of prematurity. Invest. Ophthalmol. Vis. Sci. 2013;54(15):612.
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Cystoid macular edema (CME) is a known complication of panretinal laser treatment in patients with diabetic retinopathy. We aim to investigate macular changes secondary to laser treatment for retinopathy of prematurity (ROP).
Retrospective analyses of spectral domain optical coherence tomography (SDOCT) images obtained as part of an Institutional Review Board approved study on infants having standard-of-care ROP screening sessions at Duke University Medical Center from January 2009 to January 2012. Thirteen of 97 enrolled infants had SDOCT imaging sessions both 1-2 weeks before as well as after laser treatment, and were included. SDOCT images were evaluated for the presence of CME.
Only one of the 13 infants had no CME preoperatively or postoperatively. Six of the 13 infants (46%) had CME in both eyes 1-2 weeks before laser treatment. One and two weeks after laser treatment all of these subjects continued to have CME in both eyes. Six infants had no CME preoperatively but developed CME in both eyes within 1-2 weeks after laser treatment. In three of the infants who had longer follow-up, it was observed that the edema resolved within two weeks after laser treatment.
There appears to be a relationship between laser treatment for severe ROP and CME. The CME seems to be transient, and its effect on visual development is unknown. Future studies could explore the relationship between CME in infancy and visual outcome in infants with severe ROP.
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