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Ivana Pereira, Suzana Matayoshi, ; COMPARISON OF 10% PHENYLEPHRINE TEST WITH MANUAL ELEVATION TEST IN PATIENTS WITH BILATERAL INVOLUTIONAL PTOSIS. Invest. Ophthalmol. Vis. Sci. 2013;54(15):6368.
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Quantify and compare changes in the positioning of the upper eyelid in eyes tested and in the contralateral eyes of patients with senile bilateral ptosis underwent instillation of 10% phenylephrine and the test of manual lifting of the affected eyelid.
A prospective clinical trial with 27 patients with bilateral involutional ptosis, which underwent two tests. The test 1 characterized by testing the manual lifting of the ptotic eyelid and observing the effect on the contralateral eyelid. The test 2 characterized the test of 10% phenylephrine, with instillation of two drops in more ptotic eye. During testing, patients were videotaped before and after instillation of the eyedrops of 10% phenylephrine (5, 10 and 15 minutes). Images were edited for analyzing measures eyelid. For statistical analysis, a model proposed was linear mixed effects.
In our study we observed a preference for females (88.88%) and the mean age was 68.51 years. In eyes underwent instillation of 10% phenylephrine, measurement of DMR1 increased up time of 10 minutes, maintaining statistically stable up to 15 minutes (1.21 + 0.60 + 0.90 mm to 2.36 mm). In the fellow eye, there was no statistical difference in the times studied, both in the contralateral eye to undergo testing 10% phenylephrine (1.61 + 1.42 + 0.56 mm to 0.56 mm), as in the contralateral eye submitted to manual lifting of the affected eyelid (1.60 + 1.48 + 0.77 mm to 0.73 mm).
In eyes underwent instillation of 10% phenylephrine, there was elevated position on eyelids in all cases until time of 10 minutes and remained stable until the time of 15 minutes, so we can say that sufficient time 10 minutes to find an instillated answer to the eye drops. In the contralateral eye, there was no statistical difference between all time points, both in the eye contralateral to undergo testing phenylephrine 10%, as in the contralateral eye submitted to manual lifting of the affected eyelid where all p values showed if above 0.01. Thus, we can say that small visual changes in eyelid position may occur in the contralateral eye in two groups, but they are not very expressive and difficult to detect on clinical examination usual. But a 10% phenylephrine test showed in large amplitude value MRD1, on the side where there was instilled, showing up clinically and statistically efficient.
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