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Liliana Werner, Caleb Morris, Shannon Stallings, Erica Liu, Anne Floyd, Andrew Ollerton, Lisa Leishman, Zachary Bodnar, Marcia Ong, Ali Akinay; Light Transmittance of Explanted Hydrophobic Acrylic Intraocular Lenses with Surface Light Scattering. Invest. Ophthalmol. Vis. Sci. 2013;54(15):834.
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© ARVO (1962-2015); The Authors (2016-present)
Surface light scattering on hydrophobic intraocular lenses (IOLs) is caused by hydration-related subsurface nanoglistenings within the acrylic IOL material. The aim of this study was to investigate the potential effect of surface light scattering on the light transmittance of single-piece hydrophobic acrylic IOLs made of AcrySof material (Alcon) with or without blue light filter (BLF).
IOLs were obtained from human cadavers (49 lenses total; 36 with BLF), and from finished-goods inventory (controls). The IOLs were explanted from the cadaver eyes and power/model matched to unused control IOLs. After removing proteins, the IOLs were allowed to hydrate for 24 hours at room temperature. Surface light scattering was then measured with a Scheimpflug camera (EAS-1000 Anterior Segment Analysis System, Nidek Ltd). Light transmittance was measured with a Perkin Elmer Lambda 35 UV/Vis spectrophotometer (single-beam configuration with RSA-PE-20 integrating sphere).
Hydrated scatter values ranged from 4.8 to 202.5 CCT for explanted IOLs with BLF and 1.5 to 11.8 CCT for controls; values ranged from 6.0 to 137.5 CCT for explanted IOLs without BLF and 3.5 to 9.7 CCT for controls. In both groups, there was a tendency for increasing scatter values with increasing postoperative time. No differences in light transmittance were observed between explanted IOLs and controls for both groups of lenses (BLF IOLs: P=0.407, Paired T-Test; Non BLF IOLs: P=0.216, Wilcoxon Signed Rank Test for Paired Data).
Although surface light scattering of explanted lenses was significantly higher than that of controls and appeared to increase with time, no effect was observed on the light transmittance of single-piece hydrophobic acrylic lenses with or without blue light filter.
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