June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Light Transmittance of Explanted Hydrophobic Acrylic Intraocular Lenses with Surface Light Scattering
Author Affiliations & Notes
  • Liliana Werner
    Ophthalmology, John A. Moran Eye Center, University of Utah, Salt Lake City, UT
  • Caleb Morris
    Ophthalmology, John A. Moran Eye Center, University of Utah, Salt Lake City, UT
  • Shannon Stallings
    Ophthalmology, John A. Moran Eye Center, University of Utah, Salt Lake City, UT
  • Erica Liu
    Ophthalmology, John A. Moran Eye Center, University of Utah, Salt Lake City, UT
  • Anne Floyd
    Ophthalmology, John A. Moran Eye Center, University of Utah, Salt Lake City, UT
  • Andrew Ollerton
    Ophthalmology, John A. Moran Eye Center, University of Utah, Salt Lake City, UT
  • Lisa Leishman
    Ophthalmology, John A. Moran Eye Center, University of Utah, Salt Lake City, UT
  • Zachary Bodnar
    Ophthalmology, John A. Moran Eye Center, University of Utah, Salt Lake City, UT
  • Marcia Ong
    Alcon Laboratories, Fort Worth, TX
  • Ali Akinay
    Alcon Laboratories, Fort Worth, TX
  • Footnotes
    Commercial Relationships Liliana Werner, Aaren Scientific (F), Abbott Medical Optics (F), Advanced Vision Science (F), Alcon Laboratories (F), Anew Optics (F), Bausch & Lomb Surgical (F), Calhoun Vision (F), Innovia (F), MRI Research (C), Powervision (C), Rayner Intraocular Lenses (F), Visiogen (C); Caleb Morris, None; Shannon Stallings, None; Erica Liu, None; Anne Floyd, None; Andrew Ollerton, None; Lisa Leishman, None; Zachary Bodnar, None; Marcia Ong, Alcon Research (E); Ali Akinay, Alcon Researh, Ltd (E)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 834. doi:
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      Liliana Werner, Caleb Morris, Shannon Stallings, Erica Liu, Anne Floyd, Andrew Ollerton, Lisa Leishman, Zachary Bodnar, Marcia Ong, Ali Akinay; Light Transmittance of Explanted Hydrophobic Acrylic Intraocular Lenses with Surface Light Scattering. Invest. Ophthalmol. Vis. Sci. 2013;54(15):834.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: Surface light scattering on hydrophobic intraocular lenses (IOLs) is caused by hydration-related subsurface nanoglistenings within the acrylic IOL material. The aim of this study was to investigate the potential effect of surface light scattering on the light transmittance of single-piece hydrophobic acrylic IOLs made of AcrySof material (Alcon) with or without blue light filter (BLF).

Methods: IOLs were obtained from human cadavers (49 lenses total; 36 with BLF), and from finished-goods inventory (controls). The IOLs were explanted from the cadaver eyes and power/model matched to unused control IOLs. After removing proteins, the IOLs were allowed to hydrate for 24 hours at room temperature. Surface light scattering was then measured with a Scheimpflug camera (EAS-1000 Anterior Segment Analysis System, Nidek Ltd). Light transmittance was measured with a Perkin Elmer Lambda 35 UV/Vis spectrophotometer (single-beam configuration with RSA-PE-20 integrating sphere).

Results: Hydrated scatter values ranged from 4.8 to 202.5 CCT for explanted IOLs with BLF and 1.5 to 11.8 CCT for controls; values ranged from 6.0 to 137.5 CCT for explanted IOLs without BLF and 3.5 to 9.7 CCT for controls. In both groups, there was a tendency for increasing scatter values with increasing postoperative time. No differences in light transmittance were observed between explanted IOLs and controls for both groups of lenses (BLF IOLs: P=0.407, Paired T-Test; Non BLF IOLs: P=0.216, Wilcoxon Signed Rank Test for Paired Data).

Conclusions: Although surface light scattering of explanted lenses was significantly higher than that of controls and appeared to increase with time, no effect was observed on the light transmittance of single-piece hydrophobic acrylic lenses with or without blue light filter.

Keywords: 567 intraocular lens • 551 imaging/image analysis: non-clinical • 599 microscopy: light/fluorescence/immunohistochemistry  
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