June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Schematic eye model based on the regression of age-dependent changes of the crystalline lens
Author Affiliations & Notes
  • Takushi Kawamorita
    Orthoptics and Visual Science, Kitasato University School, Sagamihara-shi, Japan
    Ophthalmology and Visual Science, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
  • Hiroshi Uozato
    Orthoptics and Visual Science, Kitasato University School, Sagamihara-shi, Japan
    Ophthalmology and Visual Science, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
  • Hiroshi Sasaki
    Ophthalmology, Kanazawa Medical University, Kahokugun, Japan
  • Yuko Shibata
    Ophthalmology and Visual Science, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
  • Masatsugu Kanazawa
    Ophthalmology and Visual Science, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
  • Masakazu Hirota
    Ophthalmology and Visual Science, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
  • yoona jang
    Ophthalmology and Visual Science, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
  • Shinji Arai
    Ophthalmology and Visual Science, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
  • Kimiya Shimizu
    Ophthalmology and Visual Science, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan
    Ophthalmology, Kitasato University School of Medicine, Sagamihara, Japan
  • Footnotes
    Commercial Relationships Takushi Kawamorita, None; Hiroshi Uozato, None; Hiroshi Sasaki, None; Yuko Shibata, None; Masatsugu Kanazawa, None; Masakazu Hirota, None; yoona jang, None; Shinji Arai, None; Kimiya Shimizu, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 848. doi:
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      Takushi Kawamorita, Hiroshi Uozato, Hiroshi Sasaki, Yuko Shibata, Masatsugu Kanazawa, Masakazu Hirota, yoona jang, Shinji Arai, Kimiya Shimizu; Schematic eye model based on the regression of age-dependent changes of the crystalline lens. Invest. Ophthalmol. Vis. Sci. 2013;54(15):848.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To construct a schematic eye model based on the regression of age-dependent changes of the crystalline lens and determine the effects on retinal image quality of refractive index, transmittance, scattering, and lens shape.

Methods: Optical simulation was performed using the optical design software CodeV. Three-dimensional eye models based on a modified Navarro model eye were used for the simulation. We used a number of published regression models in relation to the shape and optical characteristics of crystalline lens used. Refractive error and modulation transfer function (MTF) were calculated.

Results: With increasing refractive index of the lens nucleus (from 0 to +0.02), refractive errors showed a myopic shift (from 0 to -8.50 D). The amount of change increased in as the lens nucleus became steeper. However, with increasing refractive index of the lens cortex, refractive errors showed a hyperopic shift (from 0 to +2.33 D). As scattering angle increased (from 0 to 30 min arc), MTF decreased overall and the lens nucleus was affected the most. As transmittance at the center of the lens decreased (from 100 to 10%), MTF was increased at 250 c/mm and decreased at 100 c/mm, indicating the effect of apodization.

Conclusions: This schematic eye model based on regression of age-dependent changes of the crystalline lens should prove useful for the comparative evaluation of refractive correction methods and the development of new ophthalmic instruments.

Keywords: 676 refraction • 413 aging • 630 optical properties  
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