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Hiroshi Sasaki, Norihiro Mita, Natsuko Hatsusaka, Eri Shibuya, Mai Sasaki, mai takahashi, Yoriko Takahashi, Hiromi Osada, Kazuyuki Sasaki, Eri Kubo; Correlating visual function and size of area opacified by retrodots based on retro-illumination photography. Invest. Ophthalmol. Vis. Sci. 2013;54(15):864.
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© ARVO (1962-2015); The Authors (2016-present)
To consider the relationship between area opacified by retrodots (RD) and visual function (best corrected visual acuity (BCVA), retinal image contrast (RIC), and high-order aberration).
Subjects comprised 140 right eyes with RD (average age 69.6±7.1 yrs) excluding other types of cataract including three main types (nuclear, cortical and posterior subcapsular cataract), water clefts and lens opacities which may affect vision, and non-cataractous eye disease, among participants of Monzen Eye Study (Monzen, Wajima City, Ishikawa, Japan) from 2006 to 2012. The area opacified by RD within the 3 mm diameter area of the pupil center (under maximal mydriasis by tropicamide) was measured with anterior eye segment analysis system (EAS-100, Nidek). RIC with the 3 mm diameter pupil and total high-order aberrations (corneal, internal, ocular) with the 4 mm diameter pupil were measured by PSF analyzer (PSF-1000, Topcon) and wavefront analyzer (KR9000PW, Topcon), respectively. RIC was measure for low, middle and high frequency with optotypes 0.081logMAR, 0.423logMAR and 0.008logMAR.
Size of area opacified by RD was positively correlated with BCVA (logMAR) (p<0.05). BCVA was 0logMAR and 0.2logMAR for areas of RD 10% and 25%, respectively. There was a negative correlation between size of area opacified by RD and RIC for all three optotypes (p<0.05). RIC deteriorated by 10% as RD area increased by 10%. There was no significant correlation between area of RD and corneal, internal and ocular total high-order aberrations.
Within the area of 3 mm diameter of the pupil center, over 10% opacification by RD reduces VA to less than 0logMAR and RIC by 10%. However, a 10% opacification does not affect high-order aberration.
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