June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Prevalence of dry eye disease in elderly individuals of the French population (the MONTRACHET Study)
Author Affiliations & Notes
  • Aurore Muselier-Mathieu
    Ophthalmology, University Hospital, Dijon, France
  • Cyril Meillon
    Ophthalmology, University Hospital, Dijon, France
  • Caroline Fiet
    Epidemiology, University Hospital, Dijon, France
  • Sandrine Vinault
    Epidemiology, University Hospital, Dijon, France
  • Christine Binquet
    Epidemiology, University Hospital, Dijon, France
  • Benigne Mathieu
    Ophthalmology, University Hospital, Dijon, France
  • Christophe Tzourio
    Epidemiology, Inserm U708, University Hospital, Bordeaux, France
  • Alain Bron
    Ophthalmology, University Hospital, Dijon, France
  • Catherine Garcher
    Ophthalmology, University Hospital, Dijon, France
  • Footnotes
    Commercial Relationships Aurore Muselier-Mathieu, None; Cyril Meillon, None; Caroline Fiet, None; Sandrine Vinault, None; Christine Binquet, None; Benigne Mathieu, None; Christophe Tzourio, None; Alain Bron, Allergan (C), Bausch Lomb (C), Horus (F), Théa (C); Catherine Garcher, Alcon (C), Allergan (C), Baush and Lomb (C), Bayer Pharma (C), Novartis (C), Laboratoire Théa (C)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 877. doi:
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      Aurore Muselier-Mathieu, Cyril Meillon, Caroline Fiet, Sandrine Vinault, Christine Binquet, Benigne Mathieu, Christophe Tzourio, Alain Bron, Catherine Garcher; Prevalence of dry eye disease in elderly individuals of the French population (the MONTRACHET Study). Invest. Ophthalmol. Vis. Sci. 2013;54(15):877.

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Abstract
 
Purpose
 

To report the prevalence of dry eye in a large population-based sample of French individuals older than 75 years.

 
Methods
 

About 9000 individuals 65 years and older were included in the 3C cohort study since 1999 in 3 French cities (Bordeaux, Dijon and Montpellier). In Dijon, an additional ophthalmic examination was performed 10 years after the initial inclusions to assess the relation between systemic age-related diseases and eye diseases in the MONTRACHET Study (Maculopathy Optic Nerve nuTRition neurovAsCular and HEarT diseases). Dry eye symptoms were collected with self reported history of dry eye symptoms, use of topical medications and evaluated by the Ocular Surface Disease Index (OSDI) questionnaire. Every patient underwent ophthalmic evaluation which included Schirmer I test without anesthesia, tear film break up time measurement and fluorescein cornea1 staining evaluation. Prevalence of dry eye was evaluated with subjective criteria (history and OSDI questionnaire) and objective criteria.

 
Results
 

One thousand and twenty four subjects were included in the study. Mean age was 83.7 ± 3.8 years old. 62.9% of the patients were women (644). Prevalence of dry eye is reported in Tables 1 and 2. (Δ : Variable; BUT : Break-Up-Time; Fluo : Fluorescein staining; - : Négative; + : Positive)

 
Conclusions
 

As reported in the literature, this study shows wide variations in dry eye prevalence depending on the sign or symptoms considered.

     
Keywords: 486 cornea: tears/tear film/dry eye • 463 clinical (human) or epidemiologic studies: prevalence/incidence  
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