January 1975
Volume 14, Issue 1
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Articles  |   January 1975
Adenosine 3',5'-monophosphate increases the outflow of aqueous humor from the rabbit eye.
Investigative Ophthalmology & Visual Science January 1975, Vol.14, 40-42. doi:
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      A H Neufeld, D K Dueker, T Vegge, M L Sears; Adenosine 3',5'-monophosphate increases the outflow of aqueous humor from the rabbit eye.. Invest. Ophthalmol. Vis. Sci. 1975;14(1):40-42.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Direct administration of cyclic-AMP into the anterior chamber increases the outflow facility of the eye for aqueous humor. This is consistent with the hypothesis that catecholamines lower the intraocular pressure of the rabbit eye, at least in part, by a cyclic-AMP-mediated mechanism. This mechanism is active in the outflow channels and increases the rate at which aqueous humor leaves the anterior chamber.

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