Purchase this article with an account.
A R Gasset, T Akaboshi; Embryopathic effect of ophthalmic EDTA.. Invest. Ophthalmol. Vis. Sci. 1977;16(7):652-654.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Studies on the potential teratogenic effect of topically applied EDTA (0.1% and 3%) were undertaken because of its proven teratogenic effects when administered systemically and because of its wide use as an ophthalmic drug. Although no teratogenic effect was found for either 0.1% or 3% solution of EDTA, 3% EDTA applied topically to the eye six times a day has a significant embryopathic effect, with only 30% of the progeny remaining normal.
This PDF is available to Subscribers Only