June 1977
Volume 16, Issue 6
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Articles  |   June 1977
Intraocular axonal swelling produced by partial, immediately retrobulbar ligature of optic nerve.
Investigative Ophthalmology & Visual Science June 1977, Vol.16, 537-541. doi:
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      J D Wirtschafter, D E Slagel, W J Foxx, F J Rizzo; Intraocular axonal swelling produced by partial, immediately retrobulbar ligature of optic nerve.. Invest. Ophthalmol. Vis. Sci. 1977;16(6):537-541.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

This is the first report of an experimental intraorbital ligature producing papilledema characterized by axonal swelling and accumulation of mitochondria in the lamina retinalis of the optic disc of rhesus monkeys subjected to immediately retrobulbar ligature of a portion of the optic nerve. This is an improved technique for investigating the pathogenesis of papilledema and optic neuropathy.

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