July 1977
Volume 16, Issue 7
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Articles  |   July 1977
The effect of mannitol infusion on retinal function and oxygen tension.
Investigative Ophthalmology & Visual Science July 1977, Vol.16, 670-673. doi:
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      J T Ernest, W H Stern, J L Trimble; The effect of mannitol infusion on retinal function and oxygen tension.. Invest. Ophthalmol. Vis. Sci. 1977;16(7):670-673.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Mannitol administered intravenously in rhesus monkeys resulted in a temporary recovery of the visual evoked response (VER) after its decrease due to elevation of the intraocular pressure. Mannitol infusion caused an immediate, albeit transitory, increase in retinal oxygen tension. These changes were independent of the ocular hypotensive effect of mannitol, and we conclude that the drug is a far better agent for the treatment of acute glaucoma than heretofore believed.

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