June 1977
Volume 16, Issue 6
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Articles  |   June 1977
Treatment of Pseudomonas keratitis in the rabbit with antibiotic-steroid combinations.
Investigative Ophthalmology & Visual Science June 1977, Vol.16, 553-556. doi:
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      G M Bohigian, C S Foster; Treatment of Pseudomonas keratitis in the rabbit with antibiotic-steroid combinations.. Invest. Ophthalmol. Vis. Sci. 1977;16(6):553-556.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

It has been suggested that corticosteroids plus the effective antibiotics are more beneficial than antibiotics alone in reducing inflammation in infectious keratitis. Topical and subconjunctival corticosteroids as adjuncts to gentamicin therapy were evaluated by microbiological assay and clinical parameters in experimentally induced Pseudomonas keratitis in rabbits. Various strengths of dexamethasone given concurrently or delayed in conjunction with gentamicin therapy were studied. There was no statistically significant difference between combinations and the antibiotics alone in this experimental model.

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