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J C Besharse, J G Hollyfield; Turnover of mouse photoreceptor outer segments in constant light and darkness.. Invest. Ophthalmol. Vis. Sci. 1979;18(10):1019-1024.
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Pigmented mice differ from frogs in that lighting regime has only a small effect on rod outer segment turnover. During 8 days in constant light or darkness, disc addition measured as total displacement of a radioactive band in rod outer segments of mice which has received injections of tritiated amino acids was never modified by more than 7% compared to cyclic light controls. Disc shedding continued in each lighting regime, and as judged from outer segment dimensions, disc shedding approximately balanced disc addition.
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